Morbidity and mortality of vulvar and vaginal cancers: Impact of 2-, 4-, and 9-valent HPV vaccines

TR Buchanan, WS Graybill… - Human Vaccines & …, 2016 - Taylor & Francis
Vaginal and vulvar cancers do not account for a large proportion of gynecologic
malignancies but their impact is significant. Both vaginal and vulvar lesions have precursors …

Prophylactic vaccination against human papillomaviruses to prevent vulval and vaginal cancer and their precursors

L Xu, A Selk, SM Garland, F Bogliatto… - Expert review of …, 2019 - Taylor & Francis
Introduction: Safety and efficacy of prophylactic HPV vaccines against HPV infection and
associated cervical cancers and precursors is well documented in the literature; however …

HPV vaccination and the effects on rates of HPV-related cancers

JS Laurent, R Luckett, S Feldman - Current problems in cancer, 2018 - Elsevier
Globally, human papillomavirus (HPV) infection is one of the most common sexually
transmitted infection. HPV is linked to at least five malignancies including vulvar, vaginal …

Clinical trials of human papillomavirus vaccines and beyond

M Lehtinen, J Dillner - Nature reviews Clinical oncology, 2013 - nature.com
Human papillomavirus (HPV) is the most common sexually transmitted infectious agent; its
14 oncogenic types are causally associated with 5–10% of all cancers. The major structural …

Prevention of cervical, vaginal, and vulval cancers: role of the quadrivalent human papillomavirus (6, 11, 16, 18) recombinant vaccine

ML Diaz - International journal of women's health, 2010 - Taylor & Francis
The relationship between the human papillomavirus (HPV) and malignancies of the uterine
cervix, vagina, and vulva has been established. The development of a quadrivalent HPV …

Prevalence of human papillomavirus types in invasive vulvar cancers and vulvar intraepithelial neoplasia 3 in the United States before vaccine introduction

JW Gargano, EJ Wilkinson, ER Unger… - Journal of lower …, 2012 - journals.lww.com
Objective The study aimed to determine the baseline prevalence of human papillomavirus
(HPV) types in invasive vulvar cancer (IVC) and vulvar intraepithelial neoplasia 3 (VIN 3) …

Introducing human papillomavirus vaccines—questions remain

J Paavonen, M Lehtinen - Annals of Medicine, 2008 - Taylor & Francis
Genital human papillomavirus (HPV) infection and HPV‐associated cervical and other
anogenital cancers are significant public health problems. HPV 16 and HPV 18 are …

Human papillomavirus vaccines in development: if they're successful in clinical trials, how will they be implemented?

AR Shaw - Gynecologic oncology, 2005 - Elsevier
INTRODUCTION.: There are some 30–40 genotypes of human papillomavirus (HPV) that
cause anogenital lesions in humans, primarily cervical, vaginal, and vulvar dysplasias and …

Update on vaccination clinical trials for HPV-related disease

BK Erickson, EE Landers, WK Huh - Clinical therapeutics, 2014 - Elsevier
Background Cervical cancer remains a major cause of cancer death in women worldwide.
Moreover, human papillomavirus (HPV)-related disease of the urogenital tract (including …

Efficacy of human papillomavirus vaccines: a systematic quantitative review

LR Medeiros, DD Rosa, MI Da Rosa… - International Journal of …, 2009 - ijgc.bmj.com
Human papillomavirus (HPV) types cause approximately 70% of cervical cancer worldwide.
Two vaccines have been recently evaluated in randomized controlled trials: the bivalent …