The understanding of how short peptide assemblies transit from disorder to order remains
limited due to the lack of atomistic structures. Here, we report the cryo-EM structure of the …

In a model study to investigate the consequence of reactions of intrinsically disordered
regions (IDRs) of proteins in the context of the formation of highly ordered structures, we …

Although it is well-known proteins and their complexes are hierarchically organized and
highly ordered structures, it remains a major challenge to replicate their hierarchical self …

Often nanostructures formed by self-assembly of small molecules based on hydrophobic
interactions are rather unstable, causing morphological changes or even dissolution when …

Intrinsically disordered proteins (IDPs) exist in highly dynamic conformational ensembles,
which pose a major obstacle for drug development targeting IDPs because traditional …

Conspectus Biomolecular self-assembly is a ubiquitous occurrence in nature that gives rise
to sophisticated superstructures that enable the implementation of complex biological …

The self-assembly of designed peptides into filaments and other higher-order structures has
been the focus of intense interest because of the potential for creating new biomaterials and …

Sheds new light on intrinsically disordered proteins and peptides, including their role in
neurodegenerative diseases With the discovery of intrinsically disordered proteins and …

In this study, we perform a morphological evaluation of the diverse nanostructures formed by
varying concentration and amino acid sequence of a unique class of ultrasmall self …

Amphiphilic molecules and their self-assembled structures have long been the target of
extensive research due to their potential applications in fields ranging from materials design …