The present review summarizes recent advances in the transcriptional regulation of the
human apolipoprotein genes, focusing mostly, but not exclusively, on in-vivo studies and …

[Frontiers in Bioscience 6, d456-504, March 1, 2001] 456 TRANSCRIPTIONAL REGULATION OF
THE HUMAN APOLIPOPROTEIN GENES Vassilis Page 1 [Frontiers in Bioscience 6, d456-504 …

The transcription of eukaryotic genes is a complex biological event involving numerous
proteins—including RNA polymerase II, the proteins of the basal transcription initiation …

The gene coding for apolipoprotein AI (apoAI), a plasma protein involved in the transport of
cholesterol and other lipids in the plasma, is expressed predominantly in liver and intestine …

We have used human apolipoprotein cDNAs as hybridization probes to study the relative
abundance and distribution of apolipoprotein mRNAs in rabbit tissues by RNA blotting …

Apolipoproteins are important structural constituents of lipoprotein particles and have been
shown to participate in lipoprotein synthesis, secretion, proces sing, and catabolism. These …

Multiple cis-acting regulatory elements have been mapped within a 1-kilobase fragment
spanning nucleotides-651 through+ 356 of the human apolipoprotein E gene using a …

Atherosclerosis is the major public health problem in much of the world today. The
information summarized in this review, based on the recognized apolipoprotein structural …

Publisher Summary Transcriptional Control of the Human Apolipoprotein B Gene in Cell
Culture and in This chapter discusses the recent progress in three major areas of work, with …

Introduction 3. General transcription mechanisms 4. Organization of the apoAI gene and
transcription factors involved in its transcription 4.1. Proximal and distal regulatory elements …