[HTML][HTML] Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label …

S McCormack, DT Dunn, M Desai, DI Dolling, M Gafos… - The Lancet, 2016 - thelancet.com
Background Randomised placebo-controlled trials have shown that daily oral pre-exposure
prophylaxis (PrEP) with tenofovir–emtricitabine reduces the risk of HIV infection. However …

An analysis of baseline data from the PROUD study: an open-label randomised trial of pre-exposure prophylaxis

DI Dolling, M Desai, A McOwan, R Gilson, A Clarke… - Trials, 2016 - Springer
Abstract Background Pre-exposure prophylaxis (PrEP) has proven biological efficacy to
reduce the sexual acquisition of the human immunodeficiency virus (HIV). The PROUD …

On-demand pre-exposure prophylaxis with tenofovir disoproxil fumarate plus emtricitabine among men who have sex with men with less frequent sexual intercourse: a …

G Antoni, C Tremblay, C Delaugerre, I Charreau… - The lancet HIV, 2020 - thelancet.com
Background ANRS IPERGAY found that on-demand pre-exposure prophylaxis (PrEP) with
oral tenofovir disoproxil fumarate plus emtricitabine was associated with an 86% relative …

Daily and on-demand HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil (ANRS PREVENIR): a prospective observational cohort study

JM Molina, J Ghosn, L Assoumou, C Delaugerre… - The lancet HIV, 2022 - thelancet.com
Background There are few data available regarding the use of on-demand pre-exposure
prophylaxis (PrEP) for HIV prevention. We aimed to assess PrEP effectiveness, adherence …

Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all …

EO Murchu, L Marshall, C Teljeur, P Harrington… - BMJ open, 2022 - bmjopen.bmj.com
Objective To conduct a systematic review and meta-analysis of randomised controlled trials
(RCTs) of the effectiveness and safety of oral pre-exposure prophylaxis (PrEP) to prevent …

Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study

JM Molina, I Charreau, B Spire, L Cotte, J Chas… - The lancet HIV, 2017 - thelancet.com
Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We
implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour …

Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial

PM Murnane, C Celum, N Mugo, JD Campbell… - Aids, 2013 - journals.lww.com
Background: Daily oral antiretroviral preexposure prophylaxis (PrEP) is a promising strategy
for prevention of HIV-1 acquisition. Three clinical trials demonstrated PrEP efficacy; …

Real-world effectiveness of pre-exposure prophylaxis in men at high risk of HIV infection in France: a nested case-control study

H Jourdain, SB de Gage, D Desplas… - The Lancet Public …, 2022 - thelancet.com
Summary Background Pre-exposure prophylaxis (PrEP) has shown high efficacy in clinical
trials, but few observational studies have confirmed its effectiveness when prescribed in real …

Preexposure prophylaxis for HIV prevention: where have we been and where are we going?

JM Baeten, JE Haberer, AY Liu… - JAIDS Journal of Acquired …, 2013 - journals.lww.com
Preexposure prophylaxis (PrEP), in which HIV-uninfected persons with ongoing HIV risk use
antiretroviral medications to reduce their risk of acquiring HIV infection, is an efficacious and …

Medication adherence, condom use and sexually transmitted infections in Australian preexposure prophylaxis users

L Lal, J Audsley, DA Murphy, CK Fairley, M Stoove… - Aids, 2017 - journals.lww.com
Objective: HIV preexposure prophylaxis (PrEP) decreases risk of HIV acquisition; however,
its efficacy is closely dependent on adherence. There is also concern that the preventive …