ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum
F Reggiori, M Molinari - Physiological reviews, 2022 - journals.physiology.org
ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
[HTML][HTML] Emerging principles of selective ER autophagy
S Wilkinson - Journal of molecular biology, 2020 - Elsevier
The endoplasmic reticulum (ER) is a fundamental organelle in cellular metabolism and
signal transduction. It is subject to complex, dynamic sculpting of morphology and …
signal transduction. It is subject to complex, dynamic sculpting of morphology and …
ER-phagy, ER homeostasis, and ER quality control: implications for disease
S Ferro-Novick, F Reggiori, JL Brodsky - Trends in biochemical sciences, 2021 - cell.com
Lysosomal degradation of endoplasmic reticulum (ER) fragments by autophagy, termed ER-
phagy or reticulophagy, occurs under normal as well as stress conditions. The recent …
phagy or reticulophagy, occurs under normal as well as stress conditions. The recent …
ER‐phagy: shaping up and destressing the endoplasmic reticulum
S Wilkinson - The FEBS journal, 2019 - Wiley Online Library
The endoplasmic reticulum (ER) network has central roles in metabolism and cellular
organization. The ER undergoes dynamic alterations in morphology, molecular composition …
organization. The ER undergoes dynamic alterations in morphology, molecular composition …
ER-phagy: quality control and turnover of endoplasmic reticulum
H Chino, N Mizushima - Trends in Cell Biology, 2020 - cell.com
The endoplasmic reticulum (ER) is the largest organelle in cells and has fundamental
functions, such as folding, processing, and trafficking of proteins, cellular metabolism, and …
functions, such as folding, processing, and trafficking of proteins, cellular metabolism, and …
[HTML][HTML] Endoplasmic reticulum turnover: ER-phagy and other flavors in selective and non-selective ER clearance
I Fregno, M Molinari - F1000Research, 2018 - ncbi.nlm.nih.gov
The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells. It is
deputed to lipid and protein biosynthesis, calcium storage, and the detoxification of various …
deputed to lipid and protein biosynthesis, calcium storage, and the detoxification of various …
ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery
Selective autophagy of damaged or redundant organelles is an important mechanism for
maintaining cell homeostasis. We found previously that endoplasmic reticulum (ER) stress in …
maintaining cell homeostasis. We found previously that endoplasmic reticulum (ER) stress in …
ER-phagy at a glance
P Grumati, I Dikic, A Stolz - Journal of cell science, 2018 - journals.biologists.com
Selective autophagy represents the major quality control mechanism that ensures proper
turnover of exhausted or harmful organelles, among them the endoplasmic reticulum (ER) …
turnover of exhausted or harmful organelles, among them the endoplasmic reticulum (ER) …
ER‐phagy: selective autophagy of the endoplasmic reticulum
K Mochida, H Nakatogawa - EMBO reports, 2022 - embopress.org
Eukaryotic cells adequately control the mass and functions of organelles in various
situations. Autophagy, an intracellular degradation system, largely contributes to this …
situations. Autophagy, an intracellular degradation system, largely contributes to this …
[PDF][PDF] ER remodeling via ER-phagy
A Gubas, I Dikic - Molecular Cell, 2022 - cell.com
The endoplasmic reticulum (ER) is a hotspot for many essential cellular functions. The ER
membrane is highly dynamic, which affects many cellular processes that take place within …
membrane is highly dynamic, which affects many cellular processes that take place within …