[HTML][HTML] Healthy ageing and spermatogenesis

E Pohl, J Gromoll, J Wistuba, S Laurentino - Reproduction, 2021 - rep.bioscientifica.com
Delayed family planning and increased parental age increases the risk for infertility and
impaired offspring health. While the impact of ageing on oogenesis is well studied, on …

A germ cell‐specific ageing pattern in otherwise healthy men

S Laurentino, JF Cremers, B Horsthemke… - Aging …, 2020 - Wiley Online Library
Life‐long sperm production leads to the assumption that male fecundity remains unchanged
throughout life. However, recently it was shown that paternal age has profound …

[HTML][HTML] Testicular aging, male fertility and beyond

S Dong, C Chen, J Zhang, Y Gao, X Zeng… - Frontiers in …, 2022 - frontiersin.org
Normal spermatogenesis and sperm function are crucial for male fertility. The effects of
healthy testicular aging and testicular premature aging on spermatogenesis, sperm function …

Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells

E Pohl, V Höffken, S Schlatt, S Kliesch, J Gromoll… - …, 2019 - Wiley Online Library
Background Ageing in men is believed to be associated with fertility decline and elevated
risk of congenital disorders for the offspring. The previous studies also reported reduced …

Ageing of the male germ line

C Paul, B Robaire - Nature Reviews Urology, 2013 - nature.com
Several studies have demonstrated a decline in the male reproductive system, sperm
quality, and fertility with advancing paternal age, yet many of the biological mechanisms that …

Effects of age on male fertility

M Zitzmann - Best practice & research Clinical endocrinology & …, 2013 - Elsevier
Later parenting is considered by many to have advantages, parents-to-be may feel
themselves more stable to rear children. In addition, many men start a second family later in …

Aging and the germ line: where mortality and immortality meet

DL Jones - Stem cell reviews, 2007 - Springer
Germ cells are highly specialized cells that form gametes, and they are the only cells within
an organism that contribute genes to offspring. Germline stem cells (GSCs) sustain gamete …

Fertility and sperm quality in the aging male

S Almeida, L Rato, M Sousa, MG Alves… - Current …, 2017 - ingentaconnect.com
Parenthood at an older age is becoming a trend among men, especially in the most
developed societies. Aging has a significant impact on male fertility. Older men exhibit …

Male reproductive ageing: a radical road to ruin

RJ Aitken - Human Reproduction, 2023 - academic.oup.com
In modern post-transition societies, we are reproducing later and living longer. While the
impact of age on female reproductive function has been well studied, much less is known …

Effects of aging on male fertility?

E Plas, P Berger, M Hermann, H Pflüger - Experimental gerontology, 2000 - Elsevier
The increase in male life expectancy has raised issues concerning the impact of aging on
the endocrine system and male fertility. This review focuses on the relationship of …