This research aimed to identify potential drug compounds from the ZINC15 molecule
database that could effectively treat GnRH1R-related diseases. The study utilized molecular …

The ribosomal protein S6 kinase beta-1 (RPS6KB1), also known as p70S6 kinase, plays a
crucial role in various disease-related conditions such as diabetes, obesity, and cancer. Its …

The recent outbreak of the SARS-CoV-2 virus leading to the disease COVID 19, a global
pandemic has resulted in an unprecedented loss of life and economy worldwide. Hence …

Nowadays, breast cancer is one of the most widespread malignancies in women, and the
second leading cause of cancer death among women. The progesterone receptor (PR) is …

Cathepsin D (Cat D) is a lysosomal aspartic acid protease encoded by CTSD gene and has
significant biological roles such as degradation of extracellular and intracellular proteins …

Drug repurposing is a method to identify novel therapeutic agents from the existing drugs
and clinical compounds. In the present comprehensive work, molecular docking, virtual …

Rho-associated coiled-coil protein kinase (ROCK) is playing a vital role in the regulation of
key cellular events and also responsible for causing several pathological conditions such as …

Background: Matrix metalloproteinase-9 (MMP-9) plays a crucial role in the development
and progression of cancer. Therefore, identifying its inhibitors has enjoyed numerous …

We selected fifty one drugs already known for their potential disease treatment roles in
various studies and subjected to docking and molecular docking simulation (MDS) analyses …

GSK-3 is a member of cellular kinases with diversified functions such as cellular
differentiation, metabolic signaling, neuronal functions and apoptosis. It has been validated …