The role of GABAergic neural circuits in the pathogenesis of autism spectrum disorder
J Di, J Li, B O'Hara, I Alberts, L Xiong… - International Journal of …, 2020 - Wiley Online Library
Autism spectrum disorder (ASD) comprises a heterogeneous range of neurodevelopmental
conditions represented by symptoms including, communication and language deficits …
conditions represented by symptoms including, communication and language deficits …
GABA system dysfunction in autism and related disorders: from synapse to symptoms
Autism spectrum disorders (ASDs) are neurodevelopmental syndromes characterised by
repetitive behaviours and restricted interests, impairments in social behaviour and relations …
repetitive behaviours and restricted interests, impairments in social behaviour and relations …
Alterations of GABAergic signaling in autism spectrum disorders
R Pizzarelli, E Cherubini - Neural plasticity, 2011 - Wiley Online Library
Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …
[HTML][HTML] The role of GABAergic system in neurodevelopmental disorders: a focus on autism and epilepsy
P Sgadò, M Dunleavy, S Genovesi… - … Journal of Physiology …, 2011 - ncbi.nlm.nih.gov
Autism spectrum disorders (ASD) and epilepsy are very common neurological disorders of
childhood, with an estimated incidence of about 0.5–1% in worldwide population. ASD and …
childhood, with an estimated incidence of about 0.5–1% in worldwide population. ASD and …
[HTML][HTML] Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review
The primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) has a prominent role in
regulating neural development and function, with disruption to GABAergic signalling linked …
regulating neural development and function, with disruption to GABAergic signalling linked …
GABAergic system dysfunction in autism spectrum disorders
H Zhao, X Mao, C Zhu, X Zou, F Peng… - Frontiers in cell and …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a series of neurodevelopmental diseases
characterized by two hallmark symptoms, social communication deficits and repetitive …
characterized by two hallmark symptoms, social communication deficits and repetitive …
GABAergic cerebellar system in autism: a neuropathological and developmental perspective
GJ Blatt - International review of neurobiology, 2005 - Elsevier
Publisher Summary This chapter focuses on the cerebellar GABAergic system in autism, the
system in which neurons produce gamma-aminobutyric acid (GABA) as their output; it has …
system in which neurons produce gamma-aminobutyric acid (GABA) as their output; it has …
The neuropathology of autism
GJ Blatt - Scientifica, 2012 - Wiley Online Library
Autism is a behaviorally defined neurodevelopmental disorder that affects over 1% of new
births in the United States and about 2% of boys. The etiologies are unknown and they are …
births in the United States and about 2% of boys. The etiologies are unknown and they are …
[PDF][PDF] Suppressed GABAergic inhibition as a common factor in suspected etiologies of autism
JP Hussman - J Autism Dev Disord, 2001 - researchgate.net
The primary inhibitory and excitatory amino acid neurotransmitters are gamma-aminobutyric
acid (GABA) and glutamate, respectively. Despite their pervasiveness in brain function and …
acid (GABA) and glutamate, respectively. Despite their pervasiveness in brain function and …
The neurochemical basis for the treatment of autism spectrum disorders and Fragile X Syndrome
DR Hampson, DC Adusei, LKK Pacey - Biochemical pharmacology, 2011 - Elsevier
Autism spectrum disorders (ASD) and Fragile X Syndrome (FXS) are neurodevelopmental
disorders that share overlapping behavioral characteristics. While FXS is known to result …
disorders that share overlapping behavioral characteristics. While FXS is known to result …