Multidrug-resistant (MDR) bacteria have become a growing threat to public health. The gram-
positive Enterococcus faecium is classified by WHO as a high-priority pathogen among the …

Enterococcus faecalis is increasingly becoming an important nosocomial infection
opportunistic pathogen. E. faecalis can easily obtain drug resistance, making it difficult to be …

The misuse and overuse of antibiotics have contributed to a rapid emergence of antibiotic-
resistant bacterial pathogens. This global health threat underlines the urgent need for …

The emergence of multidrug-resistant (MDR) bacteria has risen rapidly, leading to a great
threat to global public health. A promising solution to this problem is the exploitation of …

In recent decades, the expansion of multi and extensively drug-resistant (MDR and XDR)
bacteria has reached an alarming rate, causing serious health concerns. Infections caused …

Endolysin-based therapeutics are promising antibacterial agents and can successfully
supplement the existing antibacterial drugs array. It is specifically important in the case of …

Antimicrobial resistance poses a significant global threat, reaching dangerously high levels
as reported by the World Health Organization. The emergence and rapid spread of new …

The endolysin EFm1 from the E. faecalis 002 (002) phage IME-EF1 efficiently lyses E.
faecalis, a gram-positive bacterium that severely threatens human health. Here, the structure …

Phage lytic enzymes (enzybiotics) have gained attention as prospective tools to eradicate
Gram-positive pathogens resistant to antibiotics. Attempts to purify the P16 endolysin of …

Due to the worldwide prevalence of antibiotic resistant strains, phages therapy has been
revitalized recently. In this study, an Enterococcus faecium phage named IME-EFm5 was …