In situ PD-L1 expression in oral squamous cell carcinoma is induced by heterogeneous mechanisms among patients
Y Kondo, S Suzuki, S Ono, M Goto, S Miyabe… - International Journal of …, 2022 - mdpi.com
The expression of programmed death ligand-1 (PD-L1) is controlled by complex
mechanisms. The elucidation of the molecular mechanisms of PD-L1 expression is …
mechanisms. The elucidation of the molecular mechanisms of PD-L1 expression is …
PD-L1 influences cell spreading, migration and invasion in head and neck cancer cells
J Eichberger, D Schulz, K Pscheidl, M Fiedler… - International journal of …, 2020 - mdpi.com
The programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1) axis
blockade has been implemented in advanced-stage tumor therapy for various entities …
blockade has been implemented in advanced-stage tumor therapy for various entities …
Prognostic significance of PD-L1 expression and its tumor-intrinsic functions in hypopharyngeal squamous cell carcinoma
P Cui, P Jing, X Liu, W Xu - Cancer Management and Research, 2020 - Taylor & Francis
Purpose The expression of programmed death-ligand 1 (PD-L1) is common in various solid
human cancers and it is an important therapeutic target. However, the expression pattern …
human cancers and it is an important therapeutic target. However, the expression pattern …
[HTML][HTML] Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment
M Hirai, H Kitahara, Y Kobayashi… - International …, 2017 - spandidos-publications.com
Blockade of the programmed-death 1 receptor (PD-1)/programmed-death ligand (PD-L1)
pathway efficiently reduces tumour growth and improves survival. Durable tumour …
pathway efficiently reduces tumour growth and improves survival. Durable tumour …
The PD-L1 protein expression in Chinese patients with recurrent or metastatic head and neck squamous cell carcinoma: a multi-center retrospective study
H Lu, D Kuang, L Jiang, J Yun, Q Xia, J Wang, P Duan… - Cancer Research, 2023 - AACR
Abstract Programmed death-ligand 1 (PD-L1) is a trans-membrane protein and co-inhibitory
factor of the immune response. PD-L1 can combine with its receptor (PD-1) to reduce the …
factor of the immune response. PD-L1 can combine with its receptor (PD-1) to reduce the …
Clinicopathological and prognostic analysis of PD-L1 and PD-L2 expression in surgically resected primary tongue squamous cell carcinoma
K Furukawa, G Kawasaki, T Yoshida… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: The expression of tumor-associated programmed death-ligand 1 (PD-L1)
predicts clinical responses to PD-1-directed immunotherapy. The expression levels of PD …
predicts clinical responses to PD-1-directed immunotherapy. The expression levels of PD …
[HTML][HTML] Changes in programmed death-ligand 1 expression during cisplatin treatment in patients with head and neck squamous cell carcinoma
Abstract Programmed death-ligand 1 (PD-L1) expression is regarded as a predictive marker
for anti-PD-1/PD-L1 therapy. The purpose of study was to explore the changes in PD-L1 …
for anti-PD-1/PD-L1 therapy. The purpose of study was to explore the changes in PD-L1 …
Expression of immunoregulatory molecules PD-L1 and PD-1 in oral cancer and precancerous lesions: A cohort study of Japanese patients
A Kouketsu, I Sato, M Oikawa, Y Shimizu… - Journal of Cranio …, 2019 - Elsevier
Objective An association of the programmed cell death-1 (PD-1) and its ligand PD-L1 with
various types of malignant tumors has been established. This study aimed to investigate the …
various types of malignant tumors has been established. This study aimed to investigate the …
Clinical and biological significance of PD-L1 expression within the tumor microenvironment of oral squamous cell carcinoma
H Takahashi, K Sakakura, Y Arisaka, A Tokue… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Programmed death-ligand 1 (PD-L1) expression in tumor cells is regulated
by a close interrelation between tumor and stromal cells within the tumor microenvironment …
by a close interrelation between tumor and stromal cells within the tumor microenvironment …
[HTML][HTML] Significant association of increased PD-L1 and PD-1 expression with nodal metastasis and a poor prognosis in oral squamous cell carcinoma
Y Maruse, S Kawano, T Jinno, R Matsubara… - International journal of …, 2018 - Elsevier
Programmed cell death ligand 1 (PD-L1) and its receptor PD-1 are immune checkpoint
molecules that attenuate the immune response. Blockade of PD-L1 enhances the immune …
molecules that attenuate the immune response. Blockade of PD-L1 enhances the immune …
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