Emerging mechanisms and targeted therapy of ferroptosis in cancer
H Wang, Y Cheng, C Mao, S Liu, D Xiao, J Huang… - Molecular Therapy, 2021 - cell.com
Ferroptosis is an iron-and lipid reactive oxygen species (ROS)-dependent form of
programmed cell death that is distinct from other forms of regulatory cell death at the …
programmed cell death that is distinct from other forms of regulatory cell death at the …
The relationship between ferroptosis and tumors: a novel landscape for therapeutic approach
X Xia, X Fan, M Zhao, P Zhu - Current gene therapy, 2019 - ingentaconnect.com
Background: Ferroptosis is a newly discovered form of iron-dependent oxidative cell death
characterized by lethal accumulation of lipid-based reactive oxygen species (ROS). It is …
characterized by lethal accumulation of lipid-based reactive oxygen species (ROS). It is …
Regulatory pathways and drugs associated with ferroptosis in tumors
D Wang, L Tang, Y Zhang, G Ge, X Jiang, Y Mo… - Cell Death & …, 2022 - nature.com
Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS).
The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane …
The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane …
Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies
Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
Recent progress on targeting ferroptosis for cancer therapy
G Xu, H Wang, X Li, R Huang, L Luo - Biochemical Pharmacology, 2021 - Elsevier
Ferroptosis is a new mode of cell death different from cell necrosis, autophagy, apoptosis,
and pyroptosis, which depends on the accumulation of reactive oxygen species (ROS) …
and pyroptosis, which depends on the accumulation of reactive oxygen species (ROS) …
Induction and application of ferroptosis in cancer therapy
Q Nie, Y Hu, X Yu, X Li, X Fang - Cancer Cell International, 2022 - Springer
At present, more than one cell death pathways have been found, one of which is ferroptosis.
Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid …
Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid …
Targeting ferroptosis as a vulnerability in cancer
Ferroptosis is an iron-dependent form of regulated cell death that is triggered by the toxic
build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered …
build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered …
Ferroptosis as a potential target for cancer therapy
Z Chen, W Wang, SR Abdul Razak, T Han… - Cell death & …, 2023 - nature.com
Ferroptosis is a recently discovered essential type of cell death that is mainly characterized
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …
The function and mechanism of ferroptosis in cancer
Y Wang, Z Wei, K Pan, J Li, Q Chen - Apoptosis, 2020 - Springer
Ferroptosis is a newly defined form of regulated cell death (RCD) characterized by iron
overload, lipid reactive oxygen species (ROS) accumulation, and lipid peroxidation, which is …
overload, lipid reactive oxygen species (ROS) accumulation, and lipid peroxidation, which is …
The role of ferroptosis in cancer development and treatment response
B Lu, XB Chen, MD Ying, QJ He, J Cao… - Frontiers in …, 2018 - frontiersin.org
Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell
death, which is a distinct regulated cell death comparing to other cell death. The lethal …
death, which is a distinct regulated cell death comparing to other cell death. The lethal …