Introduction A hormonal role in NSCLC development is well documented. We previously
showed that the aromatase inhibitor (AI) anastrozole decreased development of tobacco …

Increasing evidence shows that estrogens are involved in lung cancer proliferation and
progression, and most human lung tumors express estrogen receptor β (ERβ) as well as …

Lung cancer is the most common cancer in the world. It is a highly lethal disease in women
and men, and new treatments are urgently needed. Previous studies implicated a role of …

This perspective on Meireles et al.(beginning on p. 707 in this issue of the journal) discusses
the increasing evidence for the role of female steroid hormones in lung cancer development …

Lung cancer is the leading cause of cancer deaths in the United States, surpassing breast
cancer as the primary cause of cancer-related mortality in women. The goal of the present …

Lung cancer has become increasingly common in women, and gender differences in the
physiology and pathogenesis of the disease have suggested a role for estrogens. In the lung …

Estrogen signaling is critical in the progression of tumors that bear estrogen receptors. In
most patients with breast cancer, inhibitors that block interactions of estrogen with its …

Lung cancer is the leading cause of cancer mortality in both women and men worldwide but
gender differences exist in their clinical and biological manifestations. In particular, among …

Accumulating evidence shows that estrogens are protective factors in inflammatory lung
diseases and are involved in the gender-related incidence of these pathologies. The aim of …

Lung cancer (LC) is the leading cause of cancer death in men worldwide and has
significantly increased in women. Differences in non-small cell lung cancer (NSCLC) …