[PDF][PDF] A review on heterocyclic: Synthesis and their application in medicinal chemistry of imidazole moiety

M Hossain, AK Nanda - Science, 2018 - researchgate.net
In an organic chemistry, largest families of organic compounds are belongs in the
heterocyclic compounds. In our daily life important of heterocyclic compounds are of very …

[HTML][HTML] Synthesis and therapeutic potential of imidazole containing compounds

A Siwach, PK Verma - BMC chemistry, 2021 - Springer
Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen,
four hydrogen atoms, and two double bonds. It is also known as 1, 3-diazole. It contains two …

Comprehensive review in current developments of imidazole‐based medicinal chemistry

L Zhang, XM Peng, GLV Damu… - Medicinal research …, 2014 - Wiley Online Library
Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

[PDF][PDF] A review on “Imidazoles”: Their chemistry and pharmacological potentials

A Bhatnagar, PK Sharma, N Kumar - Int J PharmTech Res, 2011 - academia.edu
Introduction: Imidazole is an entity which is being synthesized in many of its derivative form
from past few years; the entity is major source of interest for many of medicinal chemist to …

An insight into the medicinal perspective of synthetic analogs of imidazole

S Rulhania, S Kumar, B Nehra, GD Gupta… - Journal of molecular …, 2021 - Elsevier
Imidazole remains a privileged heterocycle in drug discovery. Imidazole scaffold is a
ubiquitous motif that is present in several pharmacologically important drug molecules such …

Synthesis and Applications of 2‐Substituted Imidazole and Its Derivatives: A Review

DG Daraji, NP Prajapati… - Journal of Heterocyclic …, 2019 - Wiley Online Library
Imidazole and its derivatives are assigned as an exclusive and multifaceted skeleton
because of having a variety of applications in medicinal and synthetic organic chemistry as …

[PDF][PDF] Imidazole and its biological activities: A review

K Shalini, PK Sharma, N Kumar - Der Chemica Sinica, 2010 - academia.edu
Imidazole is a planer five-member heterocyclic ring with 3C and 2N atom and in ring N is
present in 1 st and 3 rd positions. The imidazole ring is a constituent of several important …

[PDF][PDF] Synthesis of imidazole derivatives and their biological activities

DH Romero, VET Heredia, O García-Barradas… - J Chem …, 2014 - researchgate.net
Imidazoles play an important role in medicinal chemistry, because many of its derivatives
have demonstrated significant biological activity. This article is a revision of the last years, of …

Imidazole: an essential edifice for the identification of new lead compounds and drug development

N Shalmali, MR Ali, S Bawa - Mini reviews in medicinal …, 2018 - ingentaconnect.com
In recent years, a drastic rise has been observed in incidences of resistance, low efficacy
rates and toxicities to various drugs used in therapeutic application. Presence of imidazole …

[HTML][HTML] Imidazole: synthesis, functionalization and physicochemical properties of a privileged structure in medicinal chemistry

HV Tolomeu, CAM Fraga - Molecules, 2023 - mdpi.com
Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …