Red blood cells are constantly exposed to reactive species under physiological or
pathological conditions or during administration of xenobiotics. Regardless of the source, its …

Background Evidence has increased suggesting that a condition of oxidative stress, due to
imbalance of oxidative/antioxidant systems, can produce alterations in important biological …

The involvement of oxygen-derived free radicals and other oxidant species in numerous
physiopathological processes makes it necessary to develop suitable analytical systems to …

As superoxide anion is of keen interest in biomedical research, it is highly desirable to have
a technique allowing its detection sensitively and specifically in biological media. If electron …

Measurement of the oxygen metabolite hydrogen peroxide (H 2 O 2) in biological fluids such
as plasma could be of interest because it might indicate participation of toxic oxygen species …

Since 1933 when Linus Pauling, a twice-honored Nobel laureate, proposed its existence
based on the theory of quantum mechanics, superoxide has gradually taken central stage in …

Abstract Background: The d-ROMs test for the evaluation of serum hydroperoxides (HP) is
simple, reliable, and cheap. Furthermore, it can easily be adapted to automated analyzers …

To provide a detailed description of the time course and the site specificity of hydroperoxide-
induced oxidative stress in red blood cells (RBCs), we have characterized the action of a …

Superoxide reductase (SOR) is an enzyme that converts superoxide into hydrogen peroxide
at a twofold higher yield than canonical superoxide dismutases (SOD). Superoxide radical …

Oxidative stress, ie, an imbalance between the production and the elimination of oxidant
species. The evaluation of oxidative stress in either healthy patients or in those who undergo …