[HTML][HTML] Regulation of the chemotaxis histidine kinase CheA: A structural perspective
Bacteria sense and respond to their environment through a highly conserved assembly of
transmembrane chemoreceptors (MCPs), the histidine kinase CheA, and the coupling …
transmembrane chemoreceptors (MCPs), the histidine kinase CheA, and the coupling …
The core signaling proteins of bacterial chemotaxis assemble to form an ultrastable complex
The chemosensory pathway of bacterial chemotaxis forms a polar signaling cluster in which
the fundamental signaling units, the ternary complexes, are arrayed in a highly cooperative …
the fundamental signaling units, the ternary complexes, are arrayed in a highly cooperative …
Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins
A Briegel, X Li, AM Bilwes, KT Hughes… - Proceedings of the …, 2012 - National Acad Sciences
Chemoreceptor arrays are supramolecular transmembrane machines of unknown structure
that allow bacteria to sense their surroundings and respond by chemotaxis. We have …
that allow bacteria to sense their surroundings and respond by chemotaxis. We have …
The source of high signal cooperativity in bacterial chemosensory arrays
GE Piñas, V Frank, A Vaknin… - Proceedings of the …, 2016 - National Acad Sciences
The Escherichia coli chemosensory system consists of large arrays of transmembrane
chemoreceptors associated with a dedicated histidine kinase, CheA, and a linker protein …
chemoreceptors associated with a dedicated histidine kinase, CheA, and a linker protein …
The 3.2 Å resolution structure of a receptor: CheA: CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial …
X Li, AD Fleetwood, C Bayas, AM Bilwes… - Biochemistry, 2013 - ACS Publications
Bacterial chemosensory arrays are composed of extended networks of chemoreceptors
(also known as methyl-accepting chemotaxis proteins, MCPs), the histidine kinase CheA …
(also known as methyl-accepting chemotaxis proteins, MCPs), the histidine kinase CheA …
Defining a key receptor–CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS …
KN Piasta, CJ Ulliman, PF Slivka, BR Crane… - Biochemistry, 2013 - ACS Publications
The three core components of the ubiquitous bacterial chemosensory array the
transmembrane chemoreceptor, the histidine kinase CheA, and the adaptor protein CheW …
transmembrane chemoreceptor, the histidine kinase CheA, and the adaptor protein CheW …
Structure, function, and on–off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide …
The ultrasensitive, ultrastable bacterial chemosensory array of Escherichia coli and
Salmonella typhimurium is representative of the large, conserved family of sensory arrays …
Salmonella typhimurium is representative of the large, conserved family of sensory arrays …
Bacterial chemoreceptors: high-performance signaling in networked arrays
Chemoreceptors are crucial components in the bacterial sensory systems that mediate
chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive dynamic range …
chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive dynamic range …
Reconstruction of the chemotaxis receptor–kinase assembly
SY Park, PP Borbat, G Gonzalez-Bonet… - Nature structural & …, 2006 - nature.com
In bacterial chemotaxis, an assembly of transmembrane receptors, the CheA histidine
kinase and the adaptor protein CheW processes environmental stimuli to regulate motility …
kinase and the adaptor protein CheW processes environmental stimuli to regulate motility …
His-tag-mediated dimerization of chemoreceptors leads to assembly of functional nanoarrays
Transmembrane chemotaxis receptors are found in bacteria in extended hexagonal arrays
stabilized by the membrane and by cytosolic binding partners, the kinase CheA and …
stabilized by the membrane and by cytosolic binding partners, the kinase CheA and …