Nerve growth factor (NGF) is able to restore spatial learning and reverse forebrain
cholinergic neuron atrophy when administered intracerebrally to behaviorally impaired aged …

Primary fibroblasts modified to secrete nerve growth factor (NGF) were implanted into the
nucleus basalis magnocellularis (NBM) of aged memory impaired rats. The NGF-producing …

Nerve growth factor (NGF) stimulates functional recovery from cognitive impairments
associated with aging, either when administered as a purified protein or by means of gene …

Administration of nerve growth factor (NGF) by intracerebroventricular infusion or
transplantation of NGF-secreting cells to the basal forebrain improves spatial memory in …

A highly NGF-secretlng cell line was generated by retroviral traneduction of a conditionally
immortalized CNS-derived neural progenitor cell line. After tranaplantation to the nucleus …

Administration of nerve growth factor (NGF) to aged or lesioned animals has been shown to
reverse the atrophy of basal forebrain cholinergic neurons and ameliorate behavioral …

Intraventricular administration of nerve growth factor (NGF) in rats has been shown to reduce
age-related atrophy of central cholinergic neurons and the accompanying memory …

Nerve growth factor (NGF) exerts both trophic (cell survival) and tropic (axonal growth-
promoting) effects on several neuronal populations. In particular, its robust ability to prevent …

Nerve growth factor (NGF) has recently been implicated as a trophic agent in the survival
and maintenance of basal forebrain cholinergic neurons. To test the hypothesis that NGF …

Aged rats, displaying impairments in spatial learning and memory associated with marked
cellular atrophy of forebrain cholinergic neurons, received intracerebroventricular infusions …