Drug delivery systems in regenerative medicine: an updated review

A Mansour, M Romani, AB Acharya, B Rahman… - Pharmaceutics, 2023 - mdpi.com
Modern drug discovery methods led to evolving new agents with significant therapeutic
potential. However, their properties, such as solubility and administration-related …

Biologics: the role of delivery systems in improved therapy

N Škalko-Basnet - Biologics: Targets and Therapy, 2014 - Taylor & Francis
The beginning of the 21st century saw numerous protein and peptide therapeuticals both on
the market and entering the final stages of clinical studies. They represent a new category of …

Delivering natural products and biotherapeutics to improve drug efficacy

MA Obeid, MM Al Qaraghuli, M Alsaadi… - Therapeutic …, 2017 - Taylor & Francis
Due to the increasing problem of drug resistance, new and improved medicines are
required. Natural products and biotherapeutics offer a vast resource for new drugs; however …

Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems

M Shi, KJ McHugh - Advanced Drug Delivery Reviews, 2023 - Elsevier
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Bioinspired drug delivery systems

C Alvarez-Lorenzo, A Concheiro - Current opinion in biotechnology, 2013 - Elsevier
Highlights▶ Advanced drug delivery systems (DDS) may strongly benefit from
biomimetics.▶ Natural materials are excellent models for the design and preparation of …

Advances in drug delivery systems, challenges and future directions

TC Ezike, US Okpala, UL Onoja, CP Nwike, EC Ezeako… - Heliyon, 2023 - cell.com
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

Drug delivery in biotechnology: present and future

G Orive, RM Hernandez, AR Gascón… - Current opinion in …, 2003 - Elsevier
Drug delivery is becoming a whole interdisciplinary and independent field of research and is
gaining the attention of pharmaceutical makers, medical doctors and industry. A targeted …

[HTML][HTML] Nanotechnologies for the delivery of biologicals: Historical perspective and current landscape

M Durán-Lobato, AM López-Estévez… - Advanced Drug Delivery …, 2021 - Elsevier
Biological macromolecule-based therapeutics irrupted in the pharmaceutical scene
generating a great hope due to their outstanding specificity and potency. However, given …

Protein based therapeutic delivery agents: Contemporary developments and challenges

L Yin, C Yuvienco, JK Montclare - Biomaterials, 2017 - Elsevier
As unique biopolymers, proteins can be employed for therapeutic delivery. They bear
important features such as bioavailability, biocompatibility, and biodegradability with low …

Long-term delivery of protein therapeutics

R Vaishya, V Khurana, S Patel… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Proteins are effective biotherapeutics with applications in diverse ailments.
Despite being specific and potent, their full clinical potential has not yet been realized. This …