Drug repositioning is a strategy for identifying new antitumor drugs; this strategy allows
existing and approved clinical drugs to be innovatively repurposed to treat tumors. Based on …

Drug repositioning is defined as a process to identify a new application for drugs. This
approach is critical as it takes advantage of well-known pharmacokinetics …

Tumors of the digestive system, when combined together, account for more new cases and
deaths per year than tumors arising in any other system of the body and their incidence …

Drug repurposing is a feasible strategy in developing novel medications. Regarding the
cancer field, scientists are continuously making efforts to redirect conventional drugs into …

Despite recent advances in treatment approaches, cancer is still one of the leading causes
of death worldwide. Restoration of tumor immune surveillance represents a valid strategy to …

Drug repositioning, the approach of discovering different uses for existing drugs, has gained
enormous popularity in recent years in the anticancer drug discovery field due to the …

Highlights•Neglected tropical diseases affect approximately one billion people
worldwide.•Most of the available drugs have limited efficacy and cause serious adverse …

Simple Summary Although non-prescription anthelmintics are often used for cancer
treatment, there is a lack of information regarding their anti-cancer effects in clinical settings …

Many similarities exist between cancer cells and parasites. A potentially lucrative starting
point for the discovery of novel drugs to combat parasites is to examine available …

The development of refractory tumor cells limits therapeutic efficacy in cancer by activating
mechanisms that promote cellular proliferation, migration, invasion, metastasis, and survival …