The prevention and treatment of malaria is heavily dependent on antimalarial drugs.
However, beginning with the emergence of chloroquine (CQ)-resistant Plasmodium …

Chloroquine (CQ) is the most successful antimalarial drug ever discovered. Unfortunately,
parasites resistant to the drug eventually emerged after its large scale use and are now …

Mutations in the Plasmodium falciparum 'chloroquine resistance transporter'(PfCRT) confer
resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport …

Genetic, physiological and pharmacological studies are gradually revealing the molecular
basis of chloroquine resistance (CQR) in the malaria parasite, Plasmodium falciparum …

Plasmodium falciparum resistance to chloroquine, the former gold standard antimalarial
drug, is mediated primarily by mutant forms of the chloroquine resistance transporter …

The chloroquine resistance transporter PfCRT of the human malaria parasite Plasmodium
falciparum confers resistance to the former first-line antimalarial drug chloroquine, and it …

The chloroquine resistance transporter (PfCRT) confers resistance to a wide range of
quinoline and quinoline-like antimalarial drugs in Plasmodium falciparum, with local drug …

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the
major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we …

Chloroquine (CQ) resistance in the human malaria parasite Plasmodium falciparum is
primarily conferred by mutations in the “chloroquine resistance transporter”(PfCRT). The …

Mutations in the" chloroquine resistance transporter"(PfCRT) are a major determinant of
drug resistance in the malaria parasite Plasmodium falciparum. We have previously shown …