Acute myocardial infarction (AMI) and the heart failure (HF) that often complicates this
condition, are among the leading causes of death and disability worldwide. To reduce …

Neural elements of the intrinsic cardiac nervous system transduce sensory inputs from the
heart, blood vessels and other organs to ensure adequate cardiac function on a beat-to-beat …

INTRODUCTION Acute ST-elevation myocardial infarction (STEMI) is characterised by
unpredictable epicardial artery occlusion. The myocardium supplied by the vessel is …

Acute myocardial infarction (MI) is a major cause of death worldwide. Although timely and
successful reperfusion could reduce myocardial ischemia injury, limit infarct size, and …

New findings• What is the central question of this study? Ischaemia–reperfusion of
peripheral tissues protects the heart from subsequent myocardial ischaemia–reperfusion …

Ischaemic heart disease and the heart failure that often results, remain the leading causes of
death and disability in Europe and worldwide. As such, in order to prevent heart failure and …

Background During myocardial ischemia, massive norepinephrine (NE) is released from the
cardiac sympathetic nerve terminals, reflecting the sympathetic nerve injury. A brief …

In recent decades, robust successes have been achieved in conquering the acutely lethal
manifestations of heart disease. Nevertheless, the prevalence of heart disease, especially …

The dawn of cardioprotection by infarct size reduction originated from the idea to favourably
alter the oxygen demand–supply balance of the ischaemic/infarcting myocardium by …

This review highlights the importance of neural mechanisms capable of protecting the heart
against lethal ischemia/reperfusion injury. Increased parasympathetic (vagal) activity limits …