The extracellular matrix (ECM) is a heterogeneous, connective network composed of fibrous
glycoproteins that coordinate in vivo to provide the physical scaffolding, mechanical stability …

Biologic scaffolds composed of naturally occurring extracellular matrix (ECM) have received
significant attention for their potential therapeutic applications. The full potential of the ability …

The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

The extracellular matrix (ECM) has been successfully used as a scaffold for constructive
remodeling of multiple tissues in both preclinical studies and in human clinical applications …

The extracellular matrix (ECM) regulates cell behavior by influencing cell proliferation,
survival, shape, migration and differentiation. Far from being a static structure, the ECM is …

End‐stage organ failure is a devastating problem with limited therapeutic options. The
definitive treatment is orthotropic transplantation, however, there exists a severe shortage of …

Publisher Summary This chapter describes the composition and organization of extracellular
matrix (ECM) in tissues and organs. It also identifies the utility of scaffolds derived from ECM …

Within native tissues cells are held within the extracellular matrix (ECM), which has a role in
maintaining homeostasis, guiding development and directing regeneration. Efforts in tissue …

During normal morphogenesis the extracellular matrix (ECM) influences cell motility,
proliferation, apoptosis, and differentiation. Tissue engineers have attempted to harness the …

The principles and ultimate goals of regenerative medicine and developmental biology
involve a complex sequence of events, culminating in the formation of structurally and …