Abdominal aortic aneurysms (AAA) are localized expansions of the abdominal aorta that
develop due to chronic proteolytic disruption of the structural extracellular matrix (ECM) …

Extracellular vesicles (EVs) are nanosized vesicles that carry cell-specific biomolecular
information. Our previous studies showed that adult human bone marrow mesenchymal …

Abdominal aortic aneurysms (AAAs) are potentially fatal conditions that are characterized by
decreased flexibility of the aortic wall due to proteolytic loss of the structural matrix. This …

Chronic proteolytic disruption of elastic fibres within the abdominal aortic wall results in wall
vessel expansion to form rupture‐prone abdominal aortic aneurysms (AAA). Arresting AAA …

Intrinsically poor auto-regenerative repair of proteolytically-disrupted elastic matrix structures
by resident SMCs in the wall of abdominal aortic aneurysms (AAAs) prevents growth arrest …

Vascular tissue engineering is aimed at developing regenerative vascular grafts to restore
tissue function by bypassing or replacing defective arterial segments with tubular …

The network structure and biological components of natural extracellular matrix (ECM) are
indispensable for promoting tissue regeneration. Electrospun nanofibrous scaffolds have …

Abdominal aortic aneurysms (AAAs) involve slow proteolysis and loss of structural matrix
components (collagen and elastin), which lead to wall thinning, weakening and ultimate …

Abdominal aortic aneurysm (AAA) is the pathological dilation and weakening of the
abdominal aorta wall. Inflammation, degradation of the extracellular matrix (ECM) and loss …

Background Several studies demonstrated the therapeutic potential of mesenchymal stem
cell–derived exosomes (MSC-exs) based on their anti-inflammatory properties. The …