Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens

MJ Mina, T Kula, Y Leng, M Li, RD De Vries, M Knip… - Science, 2019 - science.org
Measles virus is directly responsible for more than 100,000 deaths yearly. Epidemiological
studies have associated measles with increased morbidity and mortality for years after …

Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality

MJ Mina, CJE Metcalf, RL De Swart, A Osterhaus… - Science, 2015 - science.org
Immunosuppression after measles is known to predispose people to opportunistic infections
for a period of several weeks to months. Using population-level data, we show that measles …

Measles immune suppression: lessons from the macaque model

RD De Vries, S McQuaid, G Van Amerongen, S Yüksel… - 2012 - journals.plos.org
Measles remains a significant childhood disease, and is associated with a transient immune
suppression. Paradoxically, measles virus (MV) infection also induces robust MV-specific …

Long-term measles antibody profiles following different vaccine schedules in China, a longitudinal study

Q Wang, W Wang, AK Winter, Z Zhan, M Ajelli… - Nature …, 2023 - nature.com
Characterizing the long-term kinetics of maternally derived and vaccine-induced measles
immunity is critical for informing measles immunization strategies moving forward. Based on …

A dangerous measles future looms beyond the COVID-19 pandemic

DN Durrheim, JK Andrus, S Tabassum, H Bashour… - Nature Medicine, 2021 - nature.com
To the Editor—Children are the invisible victims of the COVID-19 pandemic. Although they
have a low risk of severe COVID-19 disease and death, they are suffering disproportionate …

Measles outbreaks in a population with declining vaccine uptake

VAA Jansen, N Stollenwerk, HJ Jensen, ME Ramsay… - Science, 2003 - science.org
Measles is a highly infectious and potentially dangerous disease. Before mass vaccination
was started in the United Kingdom, measles caused an average of 100 deaths per year (1) …

Why measles deaths are surging--and coronavirus could make it worse.

L Roberts - Nature, 2020 - go.gale.com
Why measles deaths are surging -- and coronavirus could make it worse. - Document - Gale
OneFile: Health and Medicine Use this link to get back to this page. Copy Skip to Content Library …

A role for nonprotective complement-fixing antibodies with low avidity for measles virus in atypical measles

FP Polack, SJ Hoffman, G Crujeiras, DE Griffin - Nature medicine, 2003 - nature.com
In the 1960s, a formalin-inactivated measles vaccine (FIMV) predisposed recipients to
atypical measles, an immune complex–mediated disease,. To identify characteristics of the …

[HTML][HTML] Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands

BM Laksono, RD de Vries, RJ Verburgh… - Nature …, 2018 - nature.com
Measles causes a transient immune suppression, leading to increased susceptibility to
opportunistic infections. In experimentally infected non-human primates (NHPs) measles …

Measles virus, immune control, and persistence

DE Griffin, WH Lin, CH Pan - FEMS microbiology reviews, 2012 - academic.oup.com
Measles remains one of the most important causes of child morbidity and mortality
worldwide with the greatest burden in the youngest children. Most acute measles deaths are …