A novel protective effect of erythropoietin in the infarcted heart
CJ Parsa, A Matsumoto, J Kim, RU Riel… - The Journal of …, 2003 - Am Soc Clin Investig
Erythropoietin (EPO) has been shown to protect neurons from ischemic stroke, but can also
increase thrombotic events and mortality rates in patients with ischemic heart disease. We …
increase thrombotic events and mortality rates in patients with ischemic heart disease. We …
An update on the cardiac effects of erythropoietin cardioprotection by erythropoietin and the lessons learnt from studies in neuroprotection
MA Bogoyevitch - Cardiovascular research, 2004 - academic.oup.com
Erythropoietin (Epo) was once thought to act exclusively in the formation of red blood cells.
As recently reviewed by Smith et al.[Cardiovasc. Res. 59 (2003) 538–548], Epo can also act …
As recently reviewed by Smith et al.[Cardiovasc. Res. 59 (2003) 538–548], Epo can also act …
Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia‐reperfusion injury
P van der Meer, E Lipsic, RH Henning… - European Journal of …, 2004 - Wiley Online Library
Background: Recent studies show that erythropoietin (EPO) plays a protective role in brain
ischemia. In this condition, administration of EPO protects neurons from ischemic damage …
ischemia. In this condition, administration of EPO protects neurons from ischemic damage …
Protective effects of erythropoietin in cardiac ischemia: from bench to bedside
E Lipšic, RG Schoemaker, P van der Meer… - Journal of the American …, 2006 - jacc.org
Erythropoietin (EPO) is a hypoxia-induced hormone produced in the kidneys that stimulates
hematopoiesis in the bone marrow. However, recent studies have also shown important …
hematopoiesis in the bone marrow. However, recent studies have also shown important …
Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts
CJ Parsa, J Kim, RU Riel, LS Pascal… - Journal of Biological …, 2004 - ASBMB
Erythropoietin has recently been shown to have effects beyond hematopoiesis such as
prevention of neuronal and cardiac apoptosis secondary to ischemia. In this study, we …
prevention of neuronal and cardiac apoptosis secondary to ischemia. In this study, we …
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
L Calvillo, R Latini, J Kajstura, A Leri… - Proceedings of the …, 2003 - National Acad Sciences
Erythropoietin (EPO), originally identified for its critical hormonal role in promoting
erythrocyte survival and differentiation, is a member of the large and diverse cytokine …
erythrocyte survival and differentiation, is a member of the large and diverse cytokine …
Timing of erythropoietin treatment for cardioprotection in ischemia/reperfusion
E Lipšic, P van der Meer, RH Henning… - Journal of …, 2004 - journals.lww.com
Erythropoietin (EPO) is a hormone known to stimulate hematopoiesis. However, recent
research suggests additional properties of EPO, such as protection against …
research suggests additional properties of EPO, such as protection against …
Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo
AJ Bullard, P Govewalla, DM Yellon - Basic research in cardiology, 2005 - Springer
Objective Erythropoietin (EPO) is a hormone that is currently used to treat patients with renal
failure and anaemia. However, it has also been shown to protect against …
failure and anaemia. However, it has also been shown to protect against …
A systematic review and meta-analysis of erythropoietin in experimental stroke
M Jerndal, K Forsberg, ES Sena… - Journal of Cerebral …, 2010 - journals.sagepub.com
Erythropoietin (EPO) has shown promise as a neuroprotectant in animal models of ischemic
stroke. EPO is thought not only to protect neurons from cell death, but also to promote …
stroke. EPO is thought not only to protect neurons from cell death, but also to promote …
Brain‐derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK‐1/‐2 and Akt pathways
Apart from its hematopoietic function, erythropoietin (Epo) exerts neuroprotective functions in
brain hypoxia and ischemia. To examine the mechanisms mediating Epo's neuroprotective …
brain hypoxia and ischemia. To examine the mechanisms mediating Epo's neuroprotective …