Patients with cleidocranial dysplasia (CCD) caused by mutations in RUNX2 have severe
dental anomalies, including delayed or absent eruption of permanent teeth. This requires …

Cleidocranial dysplasia (CCD), a skeletal disorder characterized by delayed permanent
tooth eruption and other dental abnormalities, is caused by heterozygous RUNX2 mutations …

RUNX2 is an important osteo-specific factor with crucial functions in bone formation and
remodelling as well as resorption of teeth. Heterozygous mutation of RUNX2 can cause …

Cleidocranial dysplasia is an autosomal dominant skeletal disorder resulting from RUNX2
mutations. The influence of RUNX2 mutations on osteoclastogenesis and bone resorption …

Cleidocranial dysplasia (CCD) is a rare genetic defect caused by a heterozygous mutation
of runt-related transcription factor 2 (RUNX2), which is important for osteoblast and skeletal …

Disturbed permanent tooth eruption is common in cleidocranial dysplasia (CCD), a skeletal
disorder caused by heterozygous mutation of RUNX2, but the mechanism underlying is still …

Objectives Cleidocranial dysplasia (CCD), mainly caused by RUNX2 mutation, is a
dominantly inherited skeletal disorder with many dental abnormalities, characterized by …

Cleidocranial dysplasia (CCD) is an autosomal dominant human disorder that affects
development of bones and teeth. The dental disorders in CCD patients include formation of …

Cleidocranial dysplasia (CCD) is an autosomal‐dominant disorder caused by a lack of
function of one or more alleles of the RUNX2 gene. Mutations of the RUNX2 gene were …

Cleidocranial dysplasia (CCD) is a skeletal dysplasia caused by heterozygous mutations of
RUNX2, a gene that is essential for the mineralization of bone and tooth. We isolated …