Sperm DNA integrity is important for normal functions such as fertilization, implantation,
pregnancy and fetal development. Sperm DNA fragmentation (SDF) is more common in …

Purpose The purpose of this study is to provide a detailed protocol and quality control steps
for measuring sperm DNA fragmentation (SDF) by terminal deoxynucleotidyl transferase …

One of the challenges with the sperm DNA fragmentation results is the inconsistency and the
large variability in the results obtained by different techniques. The terminal …

Techniques for assessing sperm DNA damage are numerous and various. There are 2 main
types of assay: direct and indirect. The former directly detects the amount of sperm DNA …

Terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-nick end
labeling or the TUNEL assay is an important technique in the assessment of DNA damage …

BACKGROUND: The extent of sperm DNA fragmentation, which can be measured by the
TUNEL assay, is one of the determinants of male fertility. However, the clinical application of …

Background and Objectives: Sperm DNA fragmentation refers to any break in one or both of
the strands of DNA in the head of a sperm. The most widely used methodologies for …

BACKGROUND: One major limitation in the use of sperm DNA fragmentation as measured
by the TdT (terminal deoxynucleotidyl transferase)-mediated dUTP nick-end labelling …

Sperm DNA fragmentation (SDF) is becoming an important test to assess male infertility.
Several different tests are available, but no consensus has yet been reached as to which …

An association between DNA fragmentation in sperm determined by the terminal
deoxynucleotidyl transferase [TdT]‐mediated deoxyuridine triphosphate (dUTP) nick end …