Introduction: In the past, total thyroidectomy was usually recommended as the initial
therapeutic approach in all but the lowest risk differentiated thyroid cancers. Today, many …

Context Modern management of differentiated thyroid cancer requires individualized care
plans that tailor the intensity of therapy and follow-up to the estimated risks of recurrence …

Context Low-risk differentiated thyroid cancer (DTC) is overdiagnosed, but true incidence
has increased as well. Owing to its excellent prognosis with low morbidity and mortality …

Controversy exists over optimal management of low-risk differentiated thyroid cancer. This
controversy occurs in all aspects of management, including surgery, use of radioactive …

Risk assessment is the cornerstone of contemporary management of thyroid cancer.
Following thyroid surgery, an initial risk assessment of recurrence and disease-specific …

In the last decade, there has been a shift in paradigm regarding differentiated thyroid cancer
staging and management from a standardized approach to an individualized way of …

Risk adapted treatment recommendations are dependent on accurate predictions of the risk
of recurrence, risk of death, and likely sites of recurrence. When combined with response to …

Objective To describe a risk-adapted management paradigm for patients with differentiated
thyroid cancer. Methods A risk-stratification approach is described that combines the …

Well-differentiated thyroid carcinoma has seen a tremendous rise in global incidence over
the past three decades, largely owing to widespread screening and identification of small …

The last 10 years have seen a renewed interest in a risk-adapted approach to the
management of differentiated thyroid cancer. This review outlines a state-of-the-art approach …