[HTML][HTML] Making the case for autophagy inhibition as a therapeutic strategy in combination with androgen-targeted therapies in prostate cancer
AM Elshazly, DA Gewirtz - Cancers, 2023 - mdpi.com
Simple Summary This paper is one in a series of articles that investigate the functional forms
of autophagy induced in tumor cells in response to various chemotherapeutic modalities …
of autophagy induced in tumor cells in response to various chemotherapeutic modalities …
[HTML][HTML] Autophagy in prostate cancer and androgen suppression therapy
E Ziparo, S Petrungaro, ES Marini, D Starace… - International journal of …, 2013 - mdpi.com
The role of autophagy is known to be highly complex and context-dependent, leading to
both cancer suppression and progression in several tumors including melanoma, breast and …
both cancer suppression and progression in several tumors including melanoma, breast and …
Does androgen‐ablation therapy (AAT) associated autophagy have a pro‐survival effect in LNCaP human prostate cancer cells?
HL Bennett, J Stockley, JT Fleming, R Mandal… - BJU …, 2013 - Wiley Online Library
What's known on the subject? and What does the study add? Androgen‐ablation therapy
(AAT) and chemotherapy are commonly used to treat incurable prostate cancer. To improve …
(AAT) and chemotherapy are commonly used to treat incurable prostate cancer. To improve …
[PDF][PDF] Prostate cancer cells at a therapeutic gunpoint of the autophagy process
F Gabriele, C Martinelli… - J. Cancer Metastasis …, 2018 - pdfs.semanticscholar.org
In a normal prostate, the process of controling cell death is essential to maintain tissue
homeostasis and its inhibition may lead to the development of cancer. Androgen receptor …
homeostasis and its inhibition may lead to the development of cancer. Androgen receptor …
Autophagy as a modulator and target in prostate cancer
JM Farrow, JC Yang, CP Evans - Nature reviews Urology, 2014 - nature.com
Abstract Autophagy, or'self-eating', is an adaptive process that enables cells to cope with
metabolic, toxic, and even infectious stressors. Although the adaptive capability of …
metabolic, toxic, and even infectious stressors. Although the adaptive capability of …
[HTML][HTML] Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft …
HG Nguyen, JC Yang, HJ Kung, XB Shi, D Tilki… - Oncogene, 2014 - nature.com
Macro-autophagy is associated with drug resistance in various cancers and can function as
an adaptive response to maintain cell survival under metabolic stresses, including androgen …
an adaptive response to maintain cell survival under metabolic stresses, including androgen …
To eat or not to eat: a critical review on the role of autophagy in prostate carcinogenesis and prostate cancer therapeutics
NJ Kurganovs, N Engedal - Frontiers in Pharmacology, 2024 - frontiersin.org
Around 1 in 7 men will be diagnosed with prostate cancer during their lifetime. Many strides
have been made in the understanding and treatment of this malignancy over the years …
have been made in the understanding and treatment of this malignancy over the years …
The role of autophagy in prostate cancer and prostatic diseases: a new therapeutic strategy
G Lemos, CMAS Fernandes, FH Silva… - Prostate Cancer and …, 2024 - nature.com
Background Autophagy is a well-conserved catabolic process that plays a key role in cell
homeostasis. In the prostate, defective autophagy has been implicated in the genesis and …
homeostasis. In the prostate, defective autophagy has been implicated in the genesis and …
[HTML][HTML] Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response
M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
Autophagy and prostate cancer therapeutics
HJ Kung, C Changou, HG Nguyen, JC Yang… - … , Molecular Biology and …, 2013 - Springer
Autophagy or self-eating is an evolutionarily conserved process whereby cells, in response
to stress conditions, use lysosomal-mediated degradation of long-lived proteins and retired …
to stress conditions, use lysosomal-mediated degradation of long-lived proteins and retired …
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