Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria
C Li, M Stražar, AMT Mohamed, JA Pacheco… - Cell, 2024 - cell.com
Accumulating evidence suggests that cardiovascular disease (CVD) is associated with an
altered gut microbiome. Our understanding of the underlying mechanisms has been …
altered gut microbiome. Our understanding of the underlying mechanisms has been …
Gut microbial associations to plasma metabolites linked to cardiovascular phenotypes and risk: a cross-sectional study
A Kurilshikov, ICL van den Munckhof, L Chen… - Circulation …, 2019 - Am Heart Assoc
Rationale: Altered gut microbial composition has been linked to cardiovascular diseases
(CVDs), but its functional links to host metabolism and immunity in relation to CVD …
(CVDs), but its functional links to host metabolism and immunity in relation to CVD …
[HTML][HTML] Cholesterol metabolism by uncultured human gut bacteria influences host cholesterol level
The human microbiome encodes extensive metabolic capabilities, but our understanding of
the mechanisms linking gut microbes to human metabolism remains limited. Here, we focus …
the mechanisms linking gut microbes to human metabolism remains limited. Here, we focus …
The gut microbiome across the cardiovascular risk spectrum
Aims Despite treatment advancements, cardiovascular disease remains a leading cause of
death worldwide. Identifying new targets is crucial for enhancing preventive and therapeutic …
death worldwide. Identifying new targets is crucial for enhancing preventive and therapeutic …
Microbial impact on cholesterol and bile acid metabolism: current status and future prospects
A Kriaa, M Bourgin, A Potiron, H Mkaouar… - Journal of lipid …, 2019 - ASBMB
Recently, the gut microbiota has emerged as a crucial factor that influences cholesterol
metabolism. Ever since, significant interest has been shown in investigating these host …
metabolism. Ever since, significant interest has been shown in investigating these host …
Metagenomic analysis of the gut microbiome in atherosclerosis patients identify cross‐cohort microbial signatures and potential therapeutic target
The gut microbiota is associated with cardiovascular diseases, including atherosclerosis.
However, the composition, functional capacity, and metabolites of the gut microbiome about …
However, the composition, functional capacity, and metabolites of the gut microbiome about …
Characterization of interactions of dietary cholesterol with the murine and human gut microbiome
Consumption of dietary lipids, such as cholesterol, modulates the gut microbiome with
consequences for host health through the production of microbiome-derived metabolites …
consequences for host health through the production of microbiome-derived metabolites …
An Integrated Metabolomic and Microbiome Analysis Identified Specific Gut Microbiota Associated with Fecal Cholesterol and Coprostanol in Clostridium difficile …
VC Antharam, DC McEwen, TJ Garrett, AT Dossey… - PloS one, 2016 - journals.plos.org
Clostridium difficile infection (CDI) is characterized by dysbiosis of the intestinal microbiota
and a profound derangement in the fecal metabolome. However, the contribution of specific …
and a profound derangement in the fecal metabolome. However, the contribution of specific …
Sequence meets function—microbiota and cardiovascular disease
The discovery that gut-microbiota plays a profound role in human health has opened a new
avenue of basic and clinical research. Application of ecological approaches where the …
avenue of basic and clinical research. Application of ecological approaches where the …
Expanding role of gut microbiota in lipid metabolism
A Ghazalpour, I Cespedes, BJ Bennett… - Current opinion in …, 2016 - journals.lww.com
Recent discoveries have broad implications for elucidating bacterially mediated
pathophysiological mechanisms that alter lipid metabolism and other related metabolic …
pathophysiological mechanisms that alter lipid metabolism and other related metabolic …