From inflammation to cancer in inflammatory bowel disease: molecular perspectives

M Romano, F De Francesco, L Zarantonello… - Anticancer …, 2016 - ar.iiarjournals.org
Inflammatory bowel diseases (IBD) are associated with an increased risk of colitis-
associated colorectal carcinoma (CAC). CAC is one of the most important causes of …

Inflammation-driven colorectal cancer associated with colitis: from pathogenesis to changing therapy

OM Nardone, I Zammarchi, G Santacroce, S Ghosh… - Cancers, 2023 - mdpi.com
Simple Summary Patients with inflammatory bowel disease (IBD) are at an increased risk of
developing colorectal cancer (CRC), mainly because of chronic intestinal inflammation …

[HTML][HTML] Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer

R Subramaniam, A Mizoguchi… - Cancer research …, 2016 - ncbi.nlm.nih.gov
To date, substantial evidence has shown a significant association between inflammatory
bowel diseases (IBD) and development of colitis-associated cancer (CAC). The …

Inflammatory bowel disease and carcinogenesis

H Nagao-Kitamoto, S Kitamoto, N Kamada - Cancer and Metastasis …, 2022 - Springer
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer mortality worldwide. Colitis-associated colorectal cancer (CAC) is a subtype …

Inflammation and colorectal cancer: colitis-associated neoplasia

SI Grivennikov - Seminars in immunopathology, 2013 - Springer
Connection between inflammation and cancer is a rapidly developing field. Epidemiological
data suggests that inflammation along with distinct arms of host immune system plays a very …

The role of inflammation in the pathogenesis of colorectal cancer

BB McConnell, VW Yang - Current colorectal cancer reports, 2009 - Springer
Chronic inflammatory disorders are often associated with an increased risk of developing
cancer. A classic example of the connection between inflammation and cancer is the …

Colitis-associated neoplasia: molecular basis and clinical translation

S Foersch, MF Neurath - Cellular and molecular life sciences, 2014 - Springer
Crohn's disease and ulcerative colitis are both associated with an increased risk of
inflammation-associated colorectal carcinoma. Colitis-associated cancer (CAC) is one of the …

[HTML][HTML] Mechanisms of immune signaling in colitis-associated cancer

MJ Waldner, MF Neurath - Cellular and molecular gastroenterology and …, 2015 - Elsevier
The inflammatory bowel diseases ulcerative colitis and Crohn's disease are associated with
an increased risk for the development of colorectal cancer. During recent years, several …

Molecular Pathways Underlying IBD-Associated Colorectal Neoplasia: Therapeutic Implications [RETRACTED]

GA Goel, A Kandiel, JP Achkar… - Official journal of the …, 2011 - journals.lww.com
Chronic inflammatory diseases, depending upon the duration and severity, are frequently
associated with an increased risk of developing cancer. A classic paradigm is the enhanced …

Clinicopathological and molecular specificities of inflammatory bowel disease–related colorectal neoplastic lesions: the role of inflammation

M Svrcek, P Borralho Nunes, V Villanacci… - Journal of Crohn's …, 2018 - academic.oup.com
Compared with the general population, patients with inflammatory bowel disease [IBD] have
an increased risk of developing colorectal cancer. Molecular mechanisms underlying …