Update on neutrophil function in severe inflammation

E Mortaz, SD Alipoor, IM Adcock, S Mumby… - Frontiers in …, 2018 - frontiersin.org
Neutrophils are main players in the effector phase of the host defense against micro-
organisms and have a major role in the innate immune response. Neutrophils show …

The diverse biological functions of neutrophils, beyond the defense against infections

F Yang, C Feng, X Zhang, J Lu, Y Zhao - Inflammation, 2017 - Springer
Polymorphonuclear neutrophils are among the first defense against infection and closely
involved in the initiation of inflammatory response. It is well recognized that this function of …

Neutrophil recruitment and function in health and inflammation

E Kolaczkowska, P Kubes - Nature reviews immunology, 2013 - nature.com
Neutrophils have traditionally been thought of as simple foot soldiers of the innate immune
system with a restricted set of pro-inflammatory functions. More recently, it has become …

[HTML][HTML] Neutrophils: their role in innate and adaptive immunity 2017

C Rosales, CA Lowell, M Schnoor… - Journal of immunology …, 2017 - ncbi.nlm.nih.gov
Neutrophils have long been regarded as the first line of defense against infection and one of
the main cell types involved in initiation of the inflammatory response. It is generally …

[HTML][HTML] Neutrophil: a cell with many roles in inflammation or several cell types?

C Rosales - Frontiers in physiology, 2018 - frontiersin.org
Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

Neutrophils: Cinderella of innate immune system

V Kumar, A Sharma - International immunopharmacology, 2010 - Elsevier
Neutrophils are the first line of innate immune defense against infectious diseases.
However, since their discovery by Elie Metchnikoff, they have always been considered …

Neutrophils at the crossroads of innate and adaptive immunity

C Rosales - Journal of Leucocyte Biology, 2020 - academic.oup.com
Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly
mobilized to sites of inflammation and/or infection. At the affected tissues, neutrophils display …

[HTML][HTML] Recent advances in understanding neutrophils

JF Deniset, P Kubes - F1000Research, 2016 - ncbi.nlm.nih.gov
Neutrophils have long been regarded as key effectors of the innate immune response during
acute inflammation. Recent evidence has revealed a greater functional diversity for these …

The role of neutrophils in immune dysfunction during severe inflammation

PHC Leliefeld, CM Wessels, LPH Leenen… - Critical care, 2016 - Springer
Critically ill post-surgical, post-trauma and/or septic patients are characterised by severe
inflammation. This immune response consists of both a pro-and an anti-inflammatory …

Regulation of immune responses by neutrophils

J Wang, H Arase - Annals of the New York Academy of …, 2014 - Wiley Online Library
Neutrophils, the most abundant circulating cells in humans, are major pathogen‐killing
immune cells. For many years, these cells were considered to be simple killers at the …