Background Colorectal cancer (CRC) is a significant public health issue, ranking as one of
the predominant cancer types globally in terms of incidence. Intriguingly, Arenobufagin …

Background Colorectal cancer (CRC) is one of the commonest cancers worldwide.
Metastasis is the most common cause of death in patients with CRC. Arenobufagin is an …

Here, we assessed the anti-colorectal cancer (CRC) cell activity of cinobufagin (CBG). We
found that CBG exerted potent cytotoxic and anti-proliferative activity against CRC lines …

Background and aims Gastric cancer is the fifth most diagnosed malignant tumor worldwide
with limited effective chemotherapy. Ferroptosis is a new type of programmed cell death …

Background It is well accepted that the immune system efficiently contributes to positive
outcomes of chemotherapeutic cancer treatment by activating immunogenic cell death (ICD) …

Colorectal cancer (CRC) has become one of the most common types of cancer with the
highest morbidity and mortality rates globally. Cinobufagin, a natural product extracted from …

Background Gastric cancer is the third leading cause of cancer-related death worldwide, for
which several novel therapeutic strategies have been developed. Cisplatin (CDDP) mainly …

Esophageal squamous cell carcinoma (ESCC) is often diagnosed at late incurable stage
and lacks effective treatment strategy. Bufadienolides are cardiotonic steroids isolated from …

Apigenin, a flavonoid, has shown early promise in colon cancer (CC); thus, exploring
potential mechanisms of Apigenin is obligatory. In this study, shared targets of Apigenin and …

Background The tumor microenvironment (TME) of hepatocellular carcinoma is
heterogeneous enough to be prone to drug resistance and multidrug resistance during …