Cost-effectiveness of bevacizumab therapy in the care of patients with hereditary hemorrhagic telangiectasia

D Wang, S Ito, C Waldron, A Butt, E Zhang… - Blood …, 2024 - ashpublications.org
Abstract No US Food and Drug Administration-or European Medicines Agency-approved
therapies exist for bleeding due to hereditary hemorrhagic telangiectasia (HHT), the second …

Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hemorrhagic hereditary telangiectasia: a national, randomized multicenter trial

S Dupuis‐Girod, S Rivière, C Lavigne… - Journal of Internal …, 2023 - Wiley Online Library
Background Bevacizumab—a humanized monoclonal antibody—has been widely used to
treat patients with hereditary hemorrhagic telangiectasia (HHT), but no randomized trial has …

[HTML][HTML] An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study

H Al-Samkari, RS Kasthuri, JG Parambil… - …, 2021 - ncbi.nlm.nih.gov
Hereditary hemorrhagic telangiectasia (HHT, Osler-Weber-Rendu disease) is a rare
multisystem vascular disorder that causes chronic gastrointestinal bleeding, epistaxis, and …

Re-treatment versus extended treatment strategy of systemic bevacizumab in hereditary hemorrhagic telangiectasia: which is better?

N Epperla, A Kleman, M Karafin, P Foy - Annals of hematology, 2018 - Springer
Dear Editor, Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant
vascular disorder characterized by a multisystem vascular dyscrasia leading to severe and …

An international survey to evaluate systemic bevacizumab for chronic bleeding in hereditary haemorrhagic telangiectasia

H Al‐Samkari, HA Albitar, SE Olitsky, MS Clancy… - …, 2020 - Wiley Online Library
Introduction Systemic bevacizumab is a novel targeted therapy for severe epistaxis and
chronic gastrointestinal bleeding in hereditary haemorrhagic telangiectasia (HHT), but …

Systemic antiangiogenic therapies for bleeding in hereditary hemorrhagic telangiectasia: a practical, evidence-based guide for clinicians

H Al-Samkari - Seminars in Thrombosis and Hemostasis, 2022 - thieme-connect.com
Management of bleeding in hereditary hemorrhagic telangiectasia (HHT), the second most
common hereditary bleeding disorder in the world, is currently undergoing a paradigm shift …

[引用][C] Even effective drugs require adequately powered trials: Systemic bevacizumab in hereditary hemorrhagic telangiectasia

H Al‐Samkari - Journal of Internal Medicine, 2023 - Wiley Online Library
In this issue of JIM, Dupuis-Girod et al. present the results of a French phase 2, randomized,
placebo-controlled trial of systemic bevacizumab to treat bleeding in 24 patients with …

[HTML][HTML] A lack of race and ethnicity data in the treatment of hereditary hemorrhagic telangiectasia: a systematic review of intravenous bevacizumab efficacy

P Galiatsatos, C Wilson, J O'Brien, AJ Gong… - Orphanet journal of rare …, 2022 - Springer
Background For extreme hereditary hemorrhagic telangiectasia (HHT) disease, treatments
such as intravenous bevacizumab are often utilized. However, whether its efficacy is similar …

[HTML][HTML] Hereditary hemorrhagic telangiectasia treated with low dose intravenous bevacizumab

JW Wee, YW Jeon, JY Eun, HJ Kim, SB Bae… - Blood …, 2014 - synapse.koreamed.org
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder that leads
to mucocutaneous telangiectasias, epistaxis, and gastrointestinal bleeding. Depending on …

Systemic bevacizumab for the treatment of chronic bleeding in hereditary haemorrhagic telangiectasia

H Al‐Samkari, A Kritharis… - Journal of internal …, 2019 - Wiley Online Library
Background Hereditary haemorrhagic telangiectasia (HHT) is a rare hereditary multisystem
vascular disorder causing visceral arteriovenous malformations and mucocutaneous …