Design, Synthesis, and Study of the Dual Action Mode of Novel N-Thienyl-1,5-disubstituted-4-pyrazole Carboxamides against Nigrospora oryzae

C Zhang, C Zhao, H Zheng, L Li… - Journal of Agricultural …, 2023 - ACS Publications
Due to the single target but extensive application of commercialized succinate
dehydrogenase inhibitors (SDHIs), resistance problems have gradually become apparent in …

Potential Fungicide Candidates: A Dual Action Mode Study of Novel Pyrazole-4-carboxamides against Gibberella zeae

C Zhang, J Yang, C Zhao, L Li, Z Wu - Journal of Agricultural and …, 2023 - ACS Publications
Pyrazole carboxamides are a class of traditional succinate dehydrogenase inhibitors
(SDHIs) that have developed into a variety of commercialized fungicides. In the present …

Design, synthesis, and antifungal activities of novel pyrazole-4-carboxamide derivatives containing an ether group as potential succinate dehydrogenase inhibitors

B Luo, Y Zhao, J Zhang, W Li, M Liu… - Journal of Agricultural …, 2023 - ACS Publications
A series of novel pyrazole-4-carboxamides bearing an ether group were designed and
synthesized on the basis of the structure of commercial succinate dehydrogenase inhibitor …

Design, synthesis, inhibitory activity, and molecular modeling of novel pyrazole-furan/thiophene carboxamide hybrids as potential fungicides targeting succinate …

W Jiang, T Zhang, J Wang, W Cheng, T Lu… - Journal of Agricultural …, 2022 - ACS Publications
To discover new fungicides targeting succinate dehydrogenase (SDH), 36 new
furan/thiophene carboxamides containing 4, 5-dihydropyrazole rings were designed …

Synthesis, Biological Evaluation, and 3D-QSAR Studies of N-(Substituted pyridine-4-yl)-1-(substituted phenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxamide …

Z Wu, HY Park, D Xie, J Yang, S Hou… - Journal of Agricultural …, 2021 - ACS Publications
A series of new fungicides that can inhibit the succinate dehydrogenase (SDH) was
classified and named as SDH inhibitors by the Fungicide Resistance Action Committee in …

Design, synthesis, DFT study and antifungal activity of the derivatives of pyrazolecarboxamide containing thiazole or oxazole ring

Z Yan, A Liu, M Huang, M Liu, H Pei, L Huang… - European Journal of …, 2018 - Elsevier
Pyrazolecarboxamide fungicides are one of the most important classes of agricultural
fungicides, which belong to succinodehydrogenase inhibitors (SDHIS). To discover new …

Discovery of novel thiazole carboxamides as antifungal succinate dehydrogenase inhibitors

X Guo, B Zhao, Z Fan, D Yang, N Zhang… - Journal of agricultural …, 2019 - ACS Publications
To contribute molecular diversity for novel fungicide development, a series of novel thiazole
carboxamides were rationally designed, synthesized, and characterized with the succinate …

Novel 4‐pyrazole carboxamide derivatives containing flexible chain motif: design, synthesis and antifungal activity

XH Liu, L Qiao, ZW Zhai, PP Cai… - Pest management …, 2019 - Wiley Online Library
Background In recent years, carboxamide fungicides, targeting succinate dehydrogenase
(SDH), have shown highly efficient and broad spectrum fungicidal activity. Structure–activity …

Novel Pyrazole-4-Carboxamide Derivatives Containing Oxime Ether Group as Potential SDHIs to Control Rhizoctonia solani

B Luo, Y Wu, X Ren, H Li, X Li, G Wang… - Journal of Agricultural …, 2024 - ACS Publications
In the search for novel succinate dehydrogenase inhibitor (SDHI) fungicides to control
Rhizoctonia solani, thirty-five novel pyrazole-4-carboxamides bearing either an oxime ether …

Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors

A Zhang, J Zhou, K Tao, T Hou, H Jin - Bioorganic & medicinal chemistry …, 2018 - Elsevier
Sixteen novel pyrazole carboxamides with diarylamines scaffold were designed,
synthesized and characterized in detail via 1 H NMR, 13 C NMR and ESI-HRMS …