In 1927 Arthur Cecil Alport, a South African physician, described a British family with an
inherited form of kidney disease that affected males more severely than females and was …

Alport syndrome (AS) is a genetic disease characterized by haematuric glomerulopathy
variably associated with hearing loss and anterior lenticonus. It is caused by mutations in the …

Alport syndrome is an inherited progressive nephropathy arising from mutations in the type
IV collagen genes, COL4A3, COL4A4, and COL4A5. Symptoms also include sensorineural …

Alport syndrome is a genetic and hereditary disease, caused by mutations in the type IV
collagen genes COL4A3, COL4A4 and COL4A5, that affects the glomerular basement …

A large tandem duplication within the COL4A5 gene is responsible for the high prevalence
of Alport syndrome in French Polynesia. Background The prevalence of X-linked Alport …

Alport syndrome is a hereditary disorder characterized by kidney disease, ocular
abnormalities, and sensorineural hearing loss. Work in understanding the cause of Alport …

Alport syndrome, historically referred to as hereditary glomerulonephritis with sensorineural
deafness and anterior lenticonus, is a genetic disease of collagen α3α4α5 (IV) resulting in …

Background. Alport syndrome (AS) is a hereditary nephropathy characterized by progressive
renal failure, hearing loss and ocular lesions. Numerous mutations of the COL4A5 gene …

Alport syndrome is a genetically and phenotypically heterogeneous disorder of glomerular,
cochlear, and ocular basement membranes resulting from mutations in the collagen IV …

Alport syndrome is a genetic disorder of basement membranes manifested clinically by a
progressive nephropathy and, in many families, sensorineural hearing loss and ocular …