The role of neutrophils in thrombosis

S Kapoor, A Opneja, L Nayak - Thrombosis research, 2018 - Elsevier
Despite significant evidence implicating an important role for neutrophils in thrombosis, their
impact on the thrombotic process has remained a matter of controversy. Until 2010, platelets …

[HTML][HTML] The emerging role of neutrophils in thrombosis—the journey of TF through NETs

K Kambas, I Mitroulis, K Ritis - Frontiers in immunology, 2012 - frontiersin.org
The production of TF by neutrophils and their contribution in thrombosis was until recently a
matter of scientific debate. Experimental data suggested the de novo TF production by …

Neutrophils: back in the thrombosis spotlight

DF Noubouossie, BN Reeves… - Blood, The Journal of …, 2019 - ashpublications.org
Reactive and clonal neutrophil expansion has been associated with thrombosis, suggesting
that neutrophils play a role in this process. However, although there is no doubt that …

The coming of age of neutrophil extracellular traps in thrombosis: Where are we now and where are we headed?

S Van Bruggen, K Martinod - Immunological Reviews, 2023 - Wiley Online Library
Thrombosis remains a major problem in our society, manifesting across multiple
demographic groups and with high associated morbidity and mortality. Thrombus …

Novel findings in neutrophil biology and their impact on cardiovascular disease

A Bonaventura, F Montecucco, F Dallegri… - Cardiovascular …, 2019 - academic.oup.com
Neutrophils are the most abundant circulating leucocytes in healthy humans. These cells are
central players during acute inflammatory responses, although a growing body of evidence …

[HTML][HTML] Propagation of thrombosis by neutrophils and extracellular nucleosome networks

S Pfeiler, K Stark, S Massberg, B Engelmann - Haematologica, 2017 - ncbi.nlm.nih.gov
Neutrophils, early mediators of the innate immune defense, are recruited to developing
thrombi in different types of thrombosis. They amplify intravascular coagulation by …

[HTML][HTML] The neutrophil's choice: phagocytose vs make neutrophil extracellular traps

AA Manfredi, GA Ramirez, P Rovere-Querini… - Frontiers in …, 2018 - frontiersin.org
Neutrophils recognize particulate substrates of microbial or endogenous origin and react by
sequestering the cargo via phagocytosis or by releasing neutrophil extracellular traps …

[HTML][HTML] The emerging role of neutrophil extracellular traps in arterial, venous and cancer-associated thrombosis

Y Zhou, W Tao, F Shen, W Du, Z Xu… - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Neutrophils play a vital role in the formation of arterial, venous and cancer-related
thrombosis. Recent studies have shown that in a process known as NETosis, neutrophils …

[HTML][HTML] Do neutrophil extracellular traps contribute to the heightened risk of thrombosis in inflammatory diseases?

AN Rao, NM Kazzaz, JS Knight - World journal of cardiology, 2015 - ncbi.nlm.nih.gov
Thrombotic events, both arterial and venous, are a major health concern worldwide. Further,
autoimmune diseases, such as systemic lupus erythematosus, anti-neutrophil cytoplasmic …

[HTML][HTML] Neutrophil extracellular traps in arterial and venous thrombosis

E Laridan, K Martinod… - Seminars in thrombosis …, 2019 - thieme-connect.com
Thrombotic complications are still a major health risk worldwide. Our view on the
pathophysiology of thrombosis has significantly changed since the discovery of neutrophil …