A pragmatic algorithm to select appropriate antiseizure medications in patients with epilepsy

AA Asadi‐Pooya, S Beniczky, G Rubboli… - …, 2020 - Wiley Online Library
Abstract Objective Antiseizure medications (ASMs) are the first‐line treatment for epilepsy.
Many ASMs are available; this offers the opportunity to improve therapy by tailoring it to …

Optimal choice of antiseizure medication: Agreement among experts and validation of a web‐based decision support application

S Beniczky, S Rampp, AA Asadi‐Pooya, G Rubboli… - …, 2021 - Wiley Online Library
Objective Optimal choice of antiseizure medication (ASM) depends on seizure type,
syndrome, age, gender, comorbidities and co‐medications. There are no fixed rules on how …

Selection of antiepileptic drugs in adults

LJ Stephen, MJ Brodie - Neurologic clinics, 2009 - neurologic.theclinics.com
Epilepsy affects approximately 50 million people worldwide, with an annual incidence of 50
to 70 cases per 100,000 population. 1 The condition can strike at any time of life, with an …

The pharmacological treatment of epilepsy in adults

T Tomson, J Zelano, YL Dang, P Perucca - Epileptic Disorders, 2023 - Wiley Online Library
The pharmacological treatment of epilepsy entails several critical decisions that need to be
based on an individual careful risk–benefit analysis. These include when to initiate treatment …

Big data analysis of ASM retention rates and expert ASM algorithm: a comparative study

S Håkansson, J Zelano - Epilepsia, 2022 - Wiley Online Library
Objective Only 50% of patients with new‐onset epilepsy achieve seizure freedom with their
first antiseizure medication (ASM). A growing body of data illustrates the complexity of …

Considerations in the choice of an antiepileptic drug in the treatment of epilepsy

NJ Azar, BW Abou-Khalil - Seminars in neurology, 2008 - thieme-connect.com
The advent of multiple new antiepileptic drugs (AEDs) in the past 15 years has provided new
options for clinicians treating patients with epilepsy, but has also created a need for …

Overview of evaluation and treatment guidelines for epilepsy

JM Stern - Current treatment options in neurology, 2009 - Springer
Opinion statement Choosing the most appropriate treatment for a patient with epilepsy
depends on complicated and critical decisions. The number of treatment options has …

[PDF][PDF] Overview of the management of epilepsy in adults

SC Schachter - UpToDate online, 2008 - cmapspublic3.ihmc.us
The management of patients with epilepsy is focused on three main goals: controlling
seizures, avoiding treatment side effects, and maintaining or restoring quality of life …

Epilepsy treatment in adults and adolescents: expert opinion, 2016

JJ Shih, JB Whitlock, N Chimato, E Vargas… - Epilepsy & Behavior, 2017 - Elsevier
Introduction: There are over twenty anti-seizure medications and anti-seizure devices
available commercially in the United States. The multitude of treatment options for seizures …

Efficacy and tolerability of antiseizure drugs

T Hakami - Therapeutic advances in neurological disorders, 2021 - journals.sagepub.com
Drug-resistant epilepsy occurs in 25–30% of patients. Furthermore, treatment with a first-
generation antiseizure drug (ASD) fails in 30–40% of individuals because of their intolerable …