[HTML][HTML] Advances in industrial biotechnology using CRISPR-Cas systems

PD Donohoue, R Barrangou, AP May - Trends in biotechnology, 2018 - cell.com
The term 'clustered regularly interspaced short palindromic repeats'(CRISPR) has recently
become synonymous with the genome-editing revolution. The RNA-guided endonuclease …

[HTML][HTML] Development and application of CRISPR/Cas in microbial biotechnology

W Ding, Y Zhang, S Shi - Frontiers in Bioengineering and …, 2020 - frontiersin.org
The clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas)
system has been rapidly developed as versatile genomic engineering tools with high …

Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics

W Liu, L Li, J Jiang, M Wu, P Lin - Precision clinical medicine, 2021 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …

CRISPR technologies for bacterial systems: current achievements and future directions

KR Choi, SY Lee - Biotechnology Advances, 2016 - Elsevier
Throughout the decades of its history, the advances in bacteria-based bio-industries have
coincided with great leaps in strain engineering technologies. Recently unveiled clustered …

Wide horizons of CRISPR-Cas-derived technologies for basic biology, agriculture, and medicine

KA Molla, S Karmakar, MT Islam - CRISPR-Cas methods, 2020 - Springer
The discovery and subsequent repurposing of the CRISPR (clustered regularly interspaced
short palindromic repeats) and Cas proteins (CRISPR-associated proteins) has …

Cas9-based tools for targeted genome editing and transcriptional control

T Xu, Y Li, JD Van Nostrand, Z He… - Applied and …, 2014 - Am Soc Microbiol
Development of tools for targeted genome editing and regulation of gene expression has
significantly expanded our ability to elucidate the mechanisms of interesting biological …

[HTML][HTML] Evolution of CRISPR/cas systems for precise genome editing

M Hryhorowicz, D Lipiński, J Zeyland - International Journal of Molecular …, 2023 - mdpi.com
The bacteria-derived CRISPR/Cas (an acronym for regularly interspaced short palindromic
repeats/CRISPR-associated protein) system is currently the most widely used, versatile, and …

[HTML][HTML] Recent advances of CRISPR/Cas9-based genetic engineering and transcriptional regulation in industrial biology

S Zhang, F Guo, W Yan, Z Dai, W Dong… - … in Bioengineering and …, 2020 - frontiersin.org
Industrial biology plays a crucial role in the fields of medicine, health, food, energy, and so
on. However, the lack of efficient genetic engineering tools has restricted the rapid …

CRISPR-Cas systems for editing, regulating and targeting genomes

JD Sander, JK Joung - Nature biotechnology, 2014 - nature.com
Targeted genome editing using engineered nucleases has rapidly gone from being a niche
technology to a mainstream method used by many biological researchers. This widespread …

[HTML][HTML] CRISPR-Cas systems for genome editing, regulation and targeting

JD Sander, JK Joung - Nature biotechnology, 2014 - ncbi.nlm.nih.gov
Targeted genome editing using engineered nucleases has rapidly transformed from a niche
technology to a mainstream method used by many biological researchers. This widespread …