Serrated polyps have been recognised in the last decade as important premalignant lesions
accounting for between 15% and 30% of colorectal cancers. There is therefore a clinical …

Approximately 30% of colorectal carcinomas develop via the serrated neoplasia pathway
characterized by widespread DNA methylation and frequent BRAF mutation. Serrated …

Serrated lesions of the colorectum are the precursors of perhaps one-third of colorectal
cancers (CRCs). Cancers arising in serrated lesions are usually in the proximal colon, and …

Background & Aims Sessile serrated polyps (SSPs) could account for a substantial
proportion of colorectal cancers. We aimed to increase clarity on SSP prevalence and …

Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Background The prevalence of sessile serrated adenomas and/or polyps (SSA/Ps) is
uncertain. Objective To determine the prevalence of SSA/Ps and SSA/Ps with cytologic …

Objective The role of serrated polyps (SPs) as colorectal cancer precursor is increasingly
recognised. However, the true prevalence SPs is largely unknown. We aimed to evaluate …

In addition to the adenoma to carcinoma sequence, colorectal carcinogenesis can occur via
the serrated pathway. Studies have focused on clarification of categories and molecular …

Colorectal cancer (CRC) is a heterogeneous disorder than arises via multiple distinct
pathways, such as the serrated pathway, in which serrated polyps (including variants of …

Background and study aims: Serrated polyps of the large intestine comprise a
heterogeneous group of lesions with distinct histological and malignant features. The aim of …