The anticarcinogen activity of β-arbutin on MCF-7 cells: Stimulation of apoptosis through estrogen receptor-α signal pathway, inflammation and genotoxicity
Ö Hazman, A Sarıova, MF Bozkurt… - Molecular and Cellular …, 2021 - Springer
Arbutin is one of the active ingredients employed in cosmetics as a skin whitening agent. In
the present study, the possible effects of arbutin on breast cancer were determined with …
the present study, the possible effects of arbutin on breast cancer were determined with …
Two faces of arbutin in hepatocellular carcinoma (HepG2) cells: Anticarcinogenic effect in high concentration and protective effect against cisplatin toxicity through its …
Arbutin is one of the active substances frequently used as a skin whitening agent in cosmetic
products. Possible effects of arbutin on hepatocellular carcinoma (HepG2) cells and cisplatin …
products. Possible effects of arbutin on hepatocellular carcinoma (HepG2) cells and cisplatin …
[HTML][HTML] The effect of arbutin on the expression of tumor suppressor P53, BAX/BCL-2 ratio and oxidative stress induced by tert-butyl hydroperoxide in fibroblast and …
S Ebadollahi, M Pouramir, E Zabihi… - Cell Journal …, 2021 - ncbi.nlm.nih.gov
Objective Arbutin (p-hydroxyphenyl-β-D-glucopyranoside) possesses beneficial functions
including antioxidant, anti-inflammatory, and anti-tumoral activities. Due to the important role …
including antioxidant, anti-inflammatory, and anti-tumoral activities. Due to the important role …
[HTML][HTML] Investigation of the pro-apoptotic effects of arbutin and its acetylated derivative on murine melanoma cells
Arbutin, a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi,
possesses whitening and anticancer properties. The effects of arbutin on melanogenesis …
possesses whitening and anticancer properties. The effects of arbutin on melanogenesis …
Arbutin exerts anticancer activity against rat C6 glioma cells by inducing apoptosis and inhibiting the inflammatory markers and P13/Akt/mTOR cascade
Z Yang, H Shi, A Chinnathambi… - … of biochemical and …, 2021 - Wiley Online Library
Gliomas are a type of brain cancer that occurs in the supporting glial cells of the brain. It is
highly malignant and accounts for 80% of brain tumors with high mortality and morbidity …
highly malignant and accounts for 80% of brain tumors with high mortality and morbidity …
Toxicogenomics of A375 human malignant melanoma cells treated with arbutin
SL Cheng, RH Liu, JN Sheu, ST Chen… - Journal of biomedical …, 2007 - Springer
Although arbutin is a natural product and widely used as an ingredient in skin care products,
its effect on the gene expression level of human skin with malignant melanoma cells is rarely …
its effect on the gene expression level of human skin with malignant melanoma cells is rarely …
Decrease of intracellular ROS by arbutin is associated with apoptosis induction and downregulation of IL‐1β and TNF‐α in LNCaP; prostate cancer
H Safari, E Zabihi, M Pouramir… - Journal of Food …, 2020 - Wiley Online Library
Increased reactive oxygen species (ROS) along with inflammation are involved in the
prostate cancer (PCa). Therefore, this study was conducted to investigate the molecular …
prostate cancer (PCa). Therefore, this study was conducted to investigate the molecular …
Alleviation effect of arbutin on oxidative stress generated through tyrosinase reaction with l-tyrosine and l-DOPA
M Tada, M Kohno, Y Niwano - BMC biochemistry, 2014 - Springer
Background Hydroxyl radical that has the highest reactivity among reactive oxygen species
(ROS) is generated through l-tyrosine-tyrosinase reaction. Thus, the melanogenesis might …
(ROS) is generated through l-tyrosine-tyrosinase reaction. Thus, the melanogenesis might …
Butein inhibits the proliferation of breast cancer cells through generation of reactive oxygen species and modulation of ERK and p38 activities
LH Yang, YJ Ho, JF Lin, CW Yeh… - Molecular …, 2012 - spandidos-publications.com
Abstract Butein (3, 4, 2', 4'-tetrahydroxychalcone) is a polyphenol derived from various
natural plants and is capable of inducing several types of death in cancer cells. However …
natural plants and is capable of inducing several types of death in cancer cells. However …
The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells
G Ma, C Yang, Y Qu, H Wei, T Zhang… - Chemico-biological …, 2007 - Elsevier
Isorhamnetin is one member of flavonoid components which has been used in the treatment
of heart disease. Recently the in vitro anti-cancer effect of isorhamnetin on human …
of heart disease. Recently the in vitro anti-cancer effect of isorhamnetin on human …
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