Novel genes in brain tissues of EAE-induced normal and obese mice: Upregulation of metal ion-binding protein genes in obese-EAE mice

M Hasan, JE Seo, KA Rahaman, H Min, KH Kim… - Neuroscience, 2017 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory autoimmune disease
of the central nervous system resulting from degeneration of the myelin sheath. This study is …

Transcriptome profiling in the hippocampi of mice with experimental autoimmune encephalomyelitis

PDE Weerasinghe-Mudiyanselage, S Kang… - International Journal of …, 2022 - mdpi.com
Experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis
(MS), approximates the key histopathological, clinical, and immunological features of MS …

mRNA expression profile reveals differentially expressed genes in splenocytes of experimental autoimmune encephalomyelitis model

A Mehmood, S Song, X Du, H Yan… - International journal …, 2023 - Wiley Online Library
Experimental autoimmune encephalomyelitis (EAE) is a mouse model that can be used to
investigate aetiology, pathogenesis, and treatment approaches for multiple sclerosis (MS). A …

Quantitative proteome analysis of brain subregions and spinal cord from experimental autoimmune encephalomyelitis mice by TMT‐based mass spectrometry

M Hasan, H Min, KA Rahaman, AR Muresan… - …, 2019 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS); its
cause is unknown. To understand the pathogenesis of MS, researchers often use the …

Increased levels of brain serotonin correlated with MMP-9 activity and IL-4 levels resulted in severe experimental autoimmune encephalomyelitis (EAE) in obese mice

M Hasan, JE Seo, KA Rahaman, MJ Kang, BH Jung… - Neuroscience, 2016 - Elsevier
The aim of this study was to investigate the role of monoamine neurotransmitters on the
severity of experimental autoimmune encephalomyelitis (EAE) in obese mice. EAE was …

Proteome analysis of brain in murine experimental autoimmune encephalomyelitis

AS Fazeli, D Nasrabadi, MH Sanati, A Pouya… - …, 2010 - Wiley Online Library
Multiple sclerosis is considered a prototype inflammatory autoimmune disorder of the CNS.
Experimental autoimmune encephalomyelitis (EAE) induced by myelin oligodendrocyte …

Key Genes in Olfactory Disorder in Experimental Autoimmune Encephalomyelitis Identified by Transcriptomic Analysis of the Olfactory Bulbs

S Hong, J Kim, M Ahn, K Jung, C Moon, C Ahn… - Molecular …, 2024 - Springer
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
that shows demyelination in the central nervous system and functional deficits, including …

Metallothioneins I/II expression in rat strains with genetically different susceptibility to experimental autoimmune encephalomyelitis

T Grubić-Kezele, H Jakovac, M Tota… - …, 2013 - karger.com
Objectives: Compared to the Dark Agouti (DA), the Albino Oxford (AO) rat strain exhibits
lower susceptibility to the induction of experimental autoimmune encephalomyelitis (EAE) …

Analysis of gene expression in MOG-induced experimental autoimmune encephalomyelitis after treatment with a novel brain-penetrating antioxidant

Y Gilgun-Sherki, Y Barhum, D Atlas, E Melamed… - Journal of molecular …, 2005 - Springer
Accumulating data from experimental studies indicate that oxidative stress has a major role
in the pathogenesis of multiple sclerosis (MS). It has been suggested that local production of …

Proteome analysis of spinal cord during the clinical course of monophasic experimental autoimmune encephalomyelitis

AS Farias, D Martins‐de‐Souza, L Guimaraes… - …, 2012 - Wiley Online Library
The induction of autoimmune encephalomyelitis (EAE) in L ewis rats results in a period of
exacerbation followed by complete recovery. Therefore, this model is widely used for …