Gene expression in keratoconus. Initial results using DNA microarrays
A Bochert, J Berlau, D Koczan, B Seitz… - Der Ophthalmologe …, 2003 - europepmc.org
Methods After examination of two corneas they were stored in RNAlater, RNA was extracted
and hybridised on the chips. Using a combination of dyes it was possible to read the chips …
and hybridised on the chips. Using a combination of dyes it was possible to read the chips …
[HTML][HTML] Evaluation of differentially expressed genes identified in keratoconus
JE Lee, BS Oum, HY Choi, SU Lee, JS Lee - Molecular vision, 2009 - ncbi.nlm.nih.gov
Methods Total RNA extracted from cultured corneal stromal fibroblasts from normal and
keratoconic corneas were used for the synthesis of cDNA. DEGs were screened by an …
keratoconic corneas were used for the synthesis of cDNA. DEGs were screened by an …
[HTML][HTML] Identification of differentially expressed genes in keratoconus epithelium analyzed on microarrays
K Nielsen, K Birkenkamp-Demtröder… - … & visual science, 2003 - arvojournals.org
purpose. The present study was conducted to investigate differential gene expression in
individual samples derived from fresh-frozen human keratoconus and normal corneal …
individual samples derived from fresh-frozen human keratoconus and normal corneal …
[HTML][HTML] Keratocan expression is increased in the stroma of keratoconus corneas
K Wentz-Hunter, EL Cheng, J Ueda, J Sugar… - Molecular …, 2001 - Springer
Background Keratoconus is a noninflammatory disease characterized by thinning and
scarring of the central portion of the cornea. The etiology is unclear. In this study, we sought …
scarring of the central portion of the cornea. The etiology is unclear. In this study, we sought …
Keratoconus
YS Rabinowitz - Survey of ophthalmology, 1998 - Elsevier
Keratoconus is a bilateral noninflammatory corneal ectasia with an incidence of
approximately 1 per 2,000 in the general population. It has well-described clinical signs, but …
approximately 1 per 2,000 in the general population. It has well-described clinical signs, but …
Omics analyses in keratoconus: From transcriptomics to proteomics
Abstract Purpose of Review To summarize the recent advances in transcriptomics and
proteomics studies of keratoconus using advanced genome-wide gene and protein …
proteomics studies of keratoconus using advanced genome-wide gene and protein …
[HTML][HTML] Abnormal regulation of extracellular matrix and adhesion molecules in corneas of patients with keratoconus
Y Bykhovskaya, A Gromova… - … of keratoconus and …, 2016 - ncbi.nlm.nih.gov
Aim To identify changes in the expression of genes coding for extracellular matrix (ECM)
proteins in patients with non-inflammatory corneal disorder keratoconus (KC), patients with …
proteins in patients with non-inflammatory corneal disorder keratoconus (KC), patients with …
[HTML][HTML] Proteomic and gene expression patterns of keratoconus
A Ghosh, L Zhou, A Ghosh, R Shetty… - Indian Journal of …, 2013 - journals.lww.com
Keratoconus is a progressive corneal thinning disease associated with significant tissue
remodeling activities and activation of a variety of signaling networks. However, it is not …
remodeling activities and activation of a variety of signaling networks. However, it is not …
[HTML][HTML] Gene expression profile studies of human keratoconus cornea for NEIBank: a novel cornea-expressed gene and the absence of transcripts for aquaporin 5
YS Rabinowitz, L Dong, G Wistow - Investigative ophthalmology & …, 2005 - arvojournals.org
purpose. To increase the database of genes expressed in human cornea and to gain
insights into the molecular basis of keratoconus (KC). methods. A cDNA library was …
insights into the molecular basis of keratoconus (KC). methods. A cDNA library was …
The elusive causes of keratoconus: a working hypothesis
CM Kenney, DJ Brown, B Rajeev - Eye & Contact Lens, 2000 - journals.lww.com
Purpose: Keratoconus is a disease that has been recognized clinically for many years.
However, it is only more recently that a better understanding has been achieved in the area …
However, it is only more recently that a better understanding has been achieved in the area …