Methods After examination of two corneas they were stored in RNAlater, RNA was extracted
and hybridised on the chips. Using a combination of dyes it was possible to read the chips …

Methods Total RNA extracted from cultured corneal stromal fibroblasts from normal and
keratoconic corneas were used for the synthesis of cDNA. DEGs were screened by an …

purpose. The present study was conducted to investigate differential gene expression in
individual samples derived from fresh-frozen human keratoconus and normal corneal …

Background Keratoconus is a noninflammatory disease characterized by thinning and
scarring of the central portion of the cornea. The etiology is unclear. In this study, we sought …

Keratoconus is a bilateral noninflammatory corneal ectasia with an incidence of
approximately 1 per 2,000 in the general population. It has well-described clinical signs, but …

Abstract Purpose of Review To summarize the recent advances in transcriptomics and
proteomics studies of keratoconus using advanced genome-wide gene and protein …

Aim To identify changes in the expression of genes coding for extracellular matrix (ECM)
proteins in patients with non-inflammatory corneal disorder keratoconus (KC), patients with …

Keratoconus is a progressive corneal thinning disease associated with significant tissue
remodeling activities and activation of a variety of signaling networks. However, it is not …

purpose. To increase the database of genes expressed in human cornea and to gain
insights into the molecular basis of keratoconus (KC). methods. A cDNA library was …

Purpose: Keratoconus is a disease that has been recognized clinically for many years.
However, it is only more recently that a better understanding has been achieved in the area …