Cytokine Signatures in Inflamed Mucosa of IBD Patients: State-of-the-Art

M Peruhova, D Miteva, M Kokudeva, S Banova… - Gastroenterology …, 2024 - mdpi.com
The process of development, recurrence, and exacerbation of the inflammatory process
depends on the cytokine levels in IBD. For that reason, many cytokine therapies have been …

Advances in understanding the role of cytokines in inflammatory bowel disease

G Bevivino, G Monteleone - Expert review of gastroenterology & …, 2018 - Taylor & Francis
Introduction: Cytokines represent the key pathophysiologic elements that govern the
initiation, progression, and, in some circumstances, the resolution of the inflammation …

[HTML][HTML] Mucosal biomarkers in inflammatory bowel disease: key pathogenic players or disease predictors?

F Scaldaferri, C Correale, A Gasbarrini… - World journal of …, 2010 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders of the bowel,
including ulcerative colitis and Crohn's disease. A single etiology has not been identified …

Cytokines in inflammatory bowel diseases–update 2020

M Leppkes, MF Neurath - Pharmacological Research, 2020 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD), namely Crohn's Disease and Ulcerative Colitis,
cause a significant disease burden in modern civilization. Ever since the introduction of anti …

Cytokines and intestinal inflammation

G Bamias, F Cominelli - Current opinion in gastroenterology, 2016 - journals.lww.com
The role of cytokines in mucosal health and disease is increasingly revealed. Such
information not only will advance our understanding of the pathogenesis of gut inflammation …

Mucosal gene expression of inflammatory cytokines as biomarkers for predicting treatment response in patients with inflammatory bowel disease

Y Yokoyama, T Yamakawa, T Miyake, T Kazama… - 2023 - researchsquare.com
Inflammatory bowel disease (IBD) is a chronic disorder that involves a complex cytokine
network. Despite an array of treatment options, no predictive biomarkers for response to IBD …

Characterization of mucosal cytokine profile in ulcerative colitis patients under conventional and anti-TNF-a treatment

LR Lopetuso, M Corbi, F Scaldaferri… - European Journal of …, 2020 - journals.lww.com
Objectives Cytokines play a pivotal role in inflammatory bowel disease (IBD). We
investigated the expression of inflammatory and regulatory cytokines in inflamed and …

[HTML][HTML] Changes of the cytokine profile in inflammatory bowel diseases

G Műzes, B Molnár, Z Tulassay… - World journal of …, 2012 - ncbi.nlm.nih.gov
Cytokines are indispensable signals of the mucosa-associated immune system for
maintaining normal gut homeostasis. An imbalance of their profile in favour of inflammation …

Inflammatory cytokines: from discoveries to therapies in IBD

I Marafini, S Sedda, V Dinallo… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Although the etiology of inflammatory bowel diseases (IBD) remains unknown,
accumulating evidence suggests that the intestinal tissue damage in these disorders is due …

[HTML][HTML] Use of Biomarkers in the Management of Inflammatory Bowel Disease

M Lewis, CM Johnson - Journal of Translational …, 2024 - xiahepublishing.com
Inflammatory bowel diseases (IBD), which include Crohn's disease and ulcerative colitis, are
chronic inflammatory disorders of the GI tract. The etiology is unclear, and most clinical …