Ferroptosis-mediated crosstalk in the tumor microenvironment implicated in cancer progression and therapy
Y Liu, C Duan, R Dai, Y Zeng - Frontiers in cell and developmental …, 2021 - frontiersin.org
Ferroptosis is a recently recognized form of non-apoptotic regulated cell death and usually
driven by iron-dependent lipid peroxidation and has arisen to play a significant role in …
driven by iron-dependent lipid peroxidation and has arisen to play a significant role in …
Ferroptosis at the crossroads of tumor-host interactions, metastasis, and therapy response
Y Yao, Y Shi, Z Gao, Y Sun, F Yao… - American Journal of …, 2022 - journals.physiology.org
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid
peroxides in an iron-dependent manner. Ferroptotic cell death is modulated by many …
peroxides in an iron-dependent manner. Ferroptotic cell death is modulated by many …
Metabolic regulation of ferroptosis in the tumor microenvironment
NE Mbah, CA Lyssiotis - Journal of Biological Chemistry, 2022 - ASBMB
Ferroptosis is an iron-dependent, nonapoptotic form of regulated cell death triggered by
impaired redox and antioxidant machinery and propagated by the accumulation of toxic lipid …
impaired redox and antioxidant machinery and propagated by the accumulation of toxic lipid …
Ferroptosis in cancer progression
R Zhang, J Chen, S Wang, W Zhang, Q Zheng, R Cai - Cells, 2023 - mdpi.com
Ferroptosis is a newly discovered iron-dependent form of regulated cell death driven by
phospholipid peroxidation and associated with processes including iron overload, lipid …
phospholipid peroxidation and associated with processes including iron overload, lipid …
Emerging mechanisms and targeted therapy of ferroptosis in cancer
H Wang, Y Cheng, C Mao, S Liu, D Xiao, J Huang… - Molecular Therapy, 2021 - cell.com
Ferroptosis is an iron-and lipid reactive oxygen species (ROS)-dependent form of
programmed cell death that is distinct from other forms of regulatory cell death at the …
programmed cell death that is distinct from other forms of regulatory cell death at the …
Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies
Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
The molecular mechanisms of regulating oxidative stress‐induced Ferroptosis and therapeutic strategy in tumors
J Zhu, Y Xiong, Y Zhang, J Wen, N Cai… - Oxidative Medicine …, 2020 - Wiley Online Library
Ferroptosis is an atypical form of regulated cell death, which is different from apoptosis,
necrosis, pyroptosis, and autophagy. Ferroptosis is characterized by iron‐dependent …
necrosis, pyroptosis, and autophagy. Ferroptosis is characterized by iron‐dependent …
Ferroptosis: a new road towards cancer management
Ferroptosis is a recently described programmed cell death mechanism that is characterized
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …
The roles of ferroptosis in cancer: tumor suppression, tumor microenvironment, and therapeutic interventions
In cancer treatment, the recurrent challenge of inducing apoptosis through conventional
therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to …
therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to …
Targeting ferroptosis as a vulnerability in cancer
Ferroptosis is an iron-dependent form of regulated cell death that is triggered by the toxic
build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered …
build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered …
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