SARS-CoV-2 membrane protein inhibits type I interferon production through ubiquitin-mediated degradation of TBK1

L Sui, Y Zhao, W Wang, P Wu, Z Wang, Y Yu… - Frontiers in …, 2021 - frontiersin.org
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative
pathogen of current COVID-19 pandemic, and insufficient production of type I interferon (IFN …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling

Y Zheng, MW Zhuang, L Han, J Zhang… - Signal transduction and …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) and spike (S) proteins antagonize host type I interferon response

Q Zhang, Z Chen, C Huang, J Sun, M Xue… - Frontiers in cellular …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has spread worldwide and has infected more than 250 million …

Activation and evasion of type I interferon responses by SARS-CoV-2

X Lei, X Dong, R Ma, W Wang, X Xiao, Z Tian… - Nature …, 2020 - nature.com
The pandemic of COVID-19 has posed an unprecedented threat to global public health.
However, the interplay between the viral pathogen of COVID-19, SARS-CoV-2, and host …

SARS-CoV-2 NSP13 inhibits type I IFN production by degradation of TBK1 via p62-dependent selective autophagy

C Sui, T Xiao, S Zhang, H Zeng, Y Zheng… - The Journal of …, 2022 - journals.aai.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease 2019 (COVID-19), has seriously threatened global public health. Severe COVID-19 …

Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling

Y Wu, L Ma, Z Zhuang, S Cai, Z Zhao, L Zhou… - Signal transduction and …, 2020 - nature.com
At present, the world is suffering from an ongoing pandemic of 2019 novel coronavirus
(COVID-19) which is caused by severe acute respiratory syndrome coronavirus 2 (SARS …

Roles and functions of SARS-CoV-2 proteins in host immune evasion

F Rashid, Z Xie, M Suleman, A Shah, S Khan… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …

SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response

YZ Fu, SY Wang, ZQ Zheng, Y Huang, WW Li… - Cellular & molecular …, 2021 - nature.com
A novel SARS-related coronavirus (SARS-CoV-2) has recently emerged as a serious
pathogen that causes high morbidity and substantial mortality. However, the mechanisms by …

The molecular mechanism of SARS-CoV-2 evading host antiviral innate immunity

W Gu, H Gan, Y Ma, L Xu, ZJ Cheng, B Li, X Zhang… - Virology journal, 2022 - Springer
Abstract The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has resulted in a global health emergency (COVID-19) because of its rapid spread …

[HTML][HTML] SARS-CoV-2 spike antagonizes innate antiviral immunity by targeting interferon regulatory factor 3

RS Freitas, TF Crum, K Parvatiyar - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Corona virus disease 2019 (COVID-19) pathogenesis is intimately linked to the severe acute
respiratory syndrome corona virus 2 (SARS-CoV-2) and disease severity has been …