Visual deficits and cognitive assessment of multiple sclerosis: confounder, correlate, or both?

D Jakimovski, RHB Benedict, B Weinstock-Guttman… - Journal of …, 2021 - Springer
Background The relationship between visual impairment and cognitive performance in
multiple sclerosis (MS) remains poorly understood. Objective To determine associations …

The temporal retinal nerve fiber layer thickness is the most important optical coherence tomography estimate in multiple sclerosis

U Birkeldh, A Manouchehrinia, MA Hietala… - Frontiers in …, 2017 - frontiersin.org
Background Reduced peripapillary retinal nerve fiber layer (pRNFL) and combined ganglion
cell and inner plexiform layer (GCIP) thicknesses as measured by optical coherence …

Visual pathway measures are associated with neuropsychological function in multiple sclerosis

J Nguyen, A Rothman, K Fitzgerald… - Current eye …, 2018 - Taylor & Francis
Purpose: To determine the relationships between visual function and ganglion cell and inner
plexiform layer thickness and neuropsychological measures in multiple sclerosis (MS) …

Visual acuity is associated with performance on visual and non-visual neuropsychological tests in multiple sclerosis

HT Feaster, JM Bruce - The Clinical Neuropsychologist, 2011 - Taylor & Francis
Both vision and cognitive problems are commonplace in multiple sclerosis. Previous
research suggests that MS patients with compromised near vision perform more poorly on …

Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than …

S Saidha, SB Syc, MK Durbin… - Multiple Sclerosis …, 2011 - journals.sagepub.com
Background: Post-mortem analyses of multiple sclerosis (MS) eyes demonstrate prominent
retinal neuronal ganglion cell layer (GCL) loss, in addition to related axonal retinal nerve …

Optical coherence tomography is associated with cognitive impairment in multiple sclerosis

S Dreyer-Alster, A Gal, A Achiron - Journal of Neuro …, 2022 - journals.lww.com
Background: Optical coherence tomography (OCT) is a sensitive method for quantifying
retinal neuronal and axonal structures. Reductions in retinal nerve fiber layer (RNFL) and …

Low contrast visual acuity testing is associated with cognitive performance in multiple sclerosis: a cross-sectional pilot study

L Wieder, G Gäde, LM Pech, H Zimmermann… - BMC neurology, 2013 - Springer
Background Cognitive impairment and visual deterioration are two key clinical symptoms in
MS and affect 50 to 80% of patients. Little is known about the influence of cognitive …

Cognitive dysfunction 24–31 years after isolated optic neuritis

P Nilsson, I Rorsman, EM Larsson… - Multiple Sclerosis …, 2008 - journals.sagepub.com
Objective Cognitive dysfunction is common in multiple sclerosis (MS), but long-term data on
cognition in patients with clinically isolated syndromes are sparse. Methods We determined …

Optical coherence tomography reflects clinically relevant gray matter damage in patients with multiple sclerosis

A Cagol, NC Fuertes, M Stoessel, M Barakovic… - Journal of …, 2023 - Springer
Background Retinal degeneration leading to optical coherence tomography (OCT) changes
is frequent in patients with multiple sclerosis (PwMS). Objective To investigate associations …

Predictors of vision impairment in multiple sclerosis

B Sanchez-Dalmau, EH Martinez-Lapiscina… - PLoS …, 2018 - journals.plos.org
Visual impairment significantly alters the quality of life of people with Multiple Sclerosis (MS).
The objective of this study was to identify predictors (independent variables) of visual …