Background: Chronic constipation is described as a common complication determined by
difficult and/or rare passage of stool or both. The difference in definition of constipation has …

Constipation is one of the major gastrointestinal disorders diagnosed in clinical practice in
Western countries. Almost 20% of population suffer from this disorder, which means …

ABSTRACT BACKGROUND Chronic constipation is a prevalent disorder that affects
patients' quality of life and consumes resources in healthcare systems worldwide. In clinical …

Chronic constipation is a common health condition representing a substantial proportion of
primary care visits and referrals to specialist providers. Chronic constipation can have a …

Background Constipation is a common, often chronic, gastrointestinal motility disorder
characterized by such symptoms as straining, hard stool, and infrequent defecation …

Abstract Constipation affects between 3% and 31% of the adult population. For most affected
persons, minimal or no intervention is required while for others, it can be challenging to treat …

Chronic constipation is a very common symptom that is rarely associated with life-
threatening diseases, but has a substantial impact on patient quality of life and consumption …

Despite its high prevalence and cost implications, our understanding of the pathophysiology
of constipation remains primitive, and available therapies have limited efficacy. The purpose …

Although chronic constipation is a common complaint, there are no ideal biological markers
for its diagnosis. Diagnosis rests on individual patient perception or clinical criteria …

Background Chronic constipation is a common, heterogeneous disorder with multiple
symptoms and pathophysiological mechanisms. Patients are often referred to a …