[HTML][HTML] Recent development of polymer nanomicelles in the treatment of eye diseases

R Cai, L Zhang, H Chi - Frontiers in bioengineering and …, 2023 - frontiersin.org
The eye, being one of the most intricate organs in the human body, hosts numerous
anatomical barriers and clearance mechanisms. This highlights the importance of devising a …

Topical application of polymeric nanomicelles in ophthalmology: a review on research efforts for the noninvasive delivery of ocular therapeutics

MA Grimaudo, S Pescina, C Padula… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction Polymeric micelles represent nowadays an interesting formulative approach for
ocular drug delivery, as they act as solubility enhancers of poorly soluble drugs and promote …

[HTML][HTML] Flexible polymeric nanosized micelles for ophthalmic drug delivery: research progress in the last three years

Z Li, M Liu, L Ke, LJ Wang, C Wu, C Li, Z Li… - Nanoscale …, 2021 - pubs.rsc.org
The eye is a complex structure with a variety of anatomical barriers and clearance
mechanisms, so the provision of safe and effective ophthalmic drug delivery technology is a …

[HTML][HTML] Drug delivery challenges and current progress in nanocarrier-based ocular therapeutic system

MH Akhter, I Ahmad, MY Alshahrani, AI Al-Harbi… - Gels, 2022 - mdpi.com
Drug instillation via a topical route is preferred since it is desirable and convenient due to the
noninvasive and easy drug access to different segments of the eye for the treatment of …

Role of polymeric micelles in Ocular Drug Delivery: an overview of decades of Research

Z Binkhathlan, R Ali, AH Alomrani… - Molecular …, 2023 - ACS Publications
Local drug delivery to the eye through conventional means has faced many challenges due
to three essential barriers:(a) the complex structure of the cornea limiting drug absorption,(b) …

[HTML][HTML] Advances in biodegradable nano-sized polymer-based ocular drug delivery

C Lynch, PPD Kondiah, YE Choonara, LC du Toit… - Polymers, 2019 - mdpi.com
The effective delivery of drugs to the eye remains a challenge. The eye has a myriad of
defense systems and physiological barriers that leaves ocular drug delivery systems with …

A review on polymers in ocular drug delivery systems

AC Bisen, A Biswas, A Dubey… - MedComm …, 2024 - Wiley Online Library
Amid the escalating prevalence of eye diseases and the intricate nature of the eye as a
crucial target organ for drug delivery, researchers face significant challenges in developing …

Exploring the advancement of polymer-based nano-formulations for ocular drug delivery systems: An explicative review

M Chakraborty, D Banerjee, S Mukherjee, D Karati - Polymer Bulletin, 2023 - Springer
The delivery of drugs to different parts of the eye through conventional approaches has been
a troublesome task for years, and the urge to overcome the disadvantages of these …

Nanomaterials for ocular drug delivery

S Liu, L Jones, FX Gu - Macromolecular bioscience, 2012 - Wiley Online Library
Efficient drug delivery to the eye remains a challenging task for pharmaceutical scientists.
Due to the various anatomical barriers and the clearance mechanisms prevailing in the eye …

Polymer-based carriers for ophthalmic drug delivery

JC Imperiale, GB Acosta, A Sosnik - Journal of controlled release, 2018 - Elsevier
Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …