Atherosclerosis is an inflammatory disease of the vessel wall characterized by monocyte
infiltration in response to pro‐atherogenic factors such as oxidized lipids. Recently, the role …

One early phase of atherosclerosis involves the recruitment of inflammatory cells from the
circulation and their transendothelial migration. This process is predominantly mediated by …

The expression of PECAM, ICAM‐1, VCAM‐1, and E‐selectin was studied in 64 samples of
human coronary arteries taken from 15 explanted hearts obtained within 5 min of …

Atherosclerosis is increasingly thought to be a chronic inflammatory disease. Inflammation
requires transmigration of leukocytes from the circulation to the tissues. Adhesion of …

Abstract P-selectin (GMP-140) is an adhesion molecule present within endothelial cells that
is rapidly translocated to the cell membrane upon activation, where it mediates endothelial …

The recruitment of mononuclear leukocytes and formation of intimal macrophage-rich
lesions at specific sites of the arterial tree are key events in atherogenesis. Inducible …

Background Leukocyte recruitment is an early event in atherogenesis, and the leukocyte
adhesion molecules E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular …

Atherosclerosis is now recognized to be an inflammatory disease, and several inflammatory
markers have been shown to be associated with both the presence and future risk of …

The progression of atherosclerosis is currently believed to involve the interaction of
monocytes with the vascular endothelium. Within the last decade, the cell-surface proteins …

Aims Inflammatory mechanisms have been implicated in the pathogenesis of
atherosclerosis. Cell adhesion molecules, expressed on endothelial cells and leukocytes …