[HTML][HTML] Signaling pathways governing breast cancer stem cells behavior

K Song, M Farzaneh - Stem Cell Research & Therapy, 2021 - Springer
Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …

[HTML][HTML] Mechanistic pathways of malignancy in breast cancer stem cells

S Yousefnia, F Seyed Forootan… - Frontiers in …, 2020 - frontiersin.org
Breast cancer stem cells (BCSCs) are the minor population of breast cancer (BC) cells that
exhibit several phenotypes such as migration, invasion, self-renewal, and chemotherapy as …

[HTML][HTML] Role, molecular mechanism and the potential target of breast cancer stem cells in breast cancer development

T Zhang, H Zhou, K Wang, X Wang, M Wang… - Biomedicine & …, 2022 - Elsevier
Breast cancer (BC) is one of the most common malignant tumors in women globally, and its
occurrence has surpassed lung cancer and become the biggest threat for women. At …

[HTML][HTML] Breast cancer stem cells—from origins to targeted therapy

WC Sin, CL Lim - Stem cell investigation, 2017 - ncbi.nlm.nih.gov
Breast cancer is marked as one of the leading causes of malignancy-related morbidities
worldwide. In spite of aggressive interventions, the inevitability of relapse and metastasis …

Review Regulation of breast cancer stem cell features

P Czerwinska, B Kaminska - Contemporary Oncology/Współczesna …, 2015 - termedia.pl
Cancer stem cells (CSCs) are rare, tumour-initiating cells that exhibit stem cell properties:
capacity of self-renewal, pluripotency, highly tumorigenic po tential, and resistance to …

Breast cancer stem cells: A review of their characteristics and the agents that affect them

NL Shan, Y Shin, G Yang, P Furmanski… - Molecular …, 2021 - Wiley Online Library
The evolving concept that cancer stem cells (CSCs) are the driving element in cancer
development, evolution and heterogeneity, has overridden the previous model of a tumor …

Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications

X Zeng, C Liu, J Yao, H Wan, G Wan, Y Li… - Pharmacological …, 2021 - Elsevier
Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …

[HTML][HTML] Breast cancer stem cells

TW Owens, MJ Naylor - Frontiers in physiology, 2013 - frontiersin.org
Cancer metastasis, resistance to therapies and disease recurrence are significant hurdles to
successful treatment of breast cancer. Identifying mechanisms by which cancer spreads …

Breast cancer stem cell: the roles and therapeutic implications

F Yang, J Xu, L Tang, X Guan - Cellular and Molecular Life Sciences, 2017 - Springer
Breast cancers have been increasingly recognized as malignancies displaying frequent
inter-and intra-tumor heterogeneity. This heterogeneity is represented by diverse subtypes …

Cancer stem cell in breast cancer therapeutic resistance

X Bai, J Ni, J Beretov, P Graham, Y Li - Cancer treatment reviews, 2018 - Elsevier
Abstract Development of therapeutic resistance and metastasis is a major challenge with
current breast cancer (BC) therapy. Mounting evidence suggests that a subpopulation of …